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Majestic Books, Hounslow, Vereinigtes Königreich
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AbeBooks-Verkäufer seit 19. Januar 2007
pp. xiv + 448 Illus. Bestandsnummer des Verkäufers 7591177
The last decade has seen a tremendous advance in our understanding of bone biology. The genes responsible for the majority of rare inherited bone disorders have been identified and much progress has been made in the identification of genes in polygenic disorders such as Paget’s disease and complex multigene diseases such as osteoporosis. Transgenic technology has identified further genes, sometimes unexpectedly, with profound effects on bone. This wealth of new genetic information will undoubtedly lead to extensive cell biological studies to understand the mechanisms by which these gene products affect bone mass and bone strength. In Bone Research Protocols a catalogue of protocols has been assembled to perform such mechanistic studies. In the tradition of the Methods in Molecular Medicine series, the chapters are practical laboratory protocols that should enable the reader to carry out the techniques from scratch. To our knowledge this is the first time such a truly practical manual on well-established bone methods has been assembled, and this volume aims to be complementary to and follow on from the more theoretical Methods in Bone Biology, edited by Arnett and Henderson (1).
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The past decade has witnessed the discovery of many genes with profound effects on bone. In Bone Research Protocols, recognized authorities with extensive hands-on experience present a wide-ranging catalog of laboratory techniques that will help researchers to investigate the mechanisms by which these genes affect bone mass and strength. Described in step-by-step detail, these readily reproducible methods cover such topics as the isolation and culture of bone cells, the preparation of bone tissue for histological and ultrastructural analysis, methods for the measurement of bone strength and for mechanical studies, and how to use digital imaging techniques in the analysis of bone. Though in vitro methods receive central attention, there are also protocols for in vivo analyses of bone formation and resorption.
State-of-the-art and highly practical, Bone Research Protocols offers both beginning and advanced laboratory researchers a major compendium of well-established techniques for studying bone cell function and metabolism.
Titel: Bone Research Protocols
Verlag: Humana Press
Erscheinungsdatum: 2003
Einband: Hardcover
Zustand: New
Anbieter: preigu, Osnabrück, Deutschland
Taschenbuch. Zustand: Neu. Bone Research Protocols | Stuart H. Ralston (u. a.) | Taschenbuch | xiv | Englisch | 2016 | Humana Press | EAN 9781493961009 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Artikel-Nr. 109583475
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Taschenbuch. Zustand: Neu. Bone Research Protocols | Stuart H. Ralston (u. a.) | Taschenbuch | xiv | Englisch | 2010 | Humana Press | EAN 9781617373213 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Artikel-Nr. 107038752
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Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
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Zustand: New. In. Artikel-Nr. ria9781617794148_new
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Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Studies over the past decade have continued to bring tremendous advances to our understanding of bone biology. New pathways have been discovered and expanded our knowledge of the ways in which genes and gene products affect bone cells and thereby bone mass and bone strength. In Bone Research Protocols, Second Edition, expert researchers in the field detail many methods commonly used to study bone biology. Focusing mainly on in vitro methods, this volume gives techniques for isolation, culture and functional analysis of all bone cell types and details a range of imaging methods, including light and ultrastructural microscopy and live cell imaging. Some important in vivo techniques are included, such as analysis of bone resorption and imaging using X rays, fluorescent or luminescent techniques. Methods for study of proteins and nucleic acid are included and methods for analysis of bone composition, measurement of bone strength, and response to mechanical stimulation are described. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Bone Research Protocols, Second Edition seeks to aid scientists in the bone field to establish new techniques in their laboratories. Artikel-Nr. 9781617794148
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Anbieter: moluna, Greven, Deutschland
Zustand: New. Contains a catalogue of protocols to assist researchers in the pursuit of mechanistic studiesProvides step-by-step detail essential for reproducible resultsContains key notes and implementation advice from the expertsContains a c. Artikel-Nr. 4259102
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Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich
Hardcover. Zustand: Brand New. 3rd edition. 740 pages. 9.25x6.10x10.00 inches. In Stock. Artikel-Nr. x-1071643053
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Zustand: New. 2025. Fourth Edition 2025. hardcover. . . . . . Books ship from the US and Ireland. Artikel-Nr. V9781071643051
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