Titel: Amyloids: Composition, Functions and Pathology (Protein Biochemistry, Synthesis, Structure and Cellular Functions: Protein Science and Engineering)
Verlag: Nova Science Pub Inc
Erscheinungsjahr: 2012
Sprache: Englisch
ISBN-10: 1621005380
ISBN-13: 9781621005384
Einband: Hardcover
Zustand: New

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Assembly and deposition of physiologically generated, amyloidogenic proteins occur in various human diseases, referred to as amyloidoses, through misfolding that is either partial unfolding or partial folding of the proteins. A growing body of evidence suggests that misfolding of a given protein is driven by point mutations or by the presence of environmental factors favourable for amyloidogenesis. In this book, the authors present topical research in the study of the composition, function and pathology of amyloids, including the effect of yeast red pigment on amyloid fibrils in vivo and in vitro; amyloid precursor protein and its relation to Alzheimer's disease; amyloid precursor protein expression after traumatic brain injury; protein aggregation as a modulatory factor in EPMI and the atomic-resolution structures of prion AGAAAAGA amyloid fibrils.

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