Molecular Structures and Structural Dynamics of Prion Proteins and Prions: Mechanism Underlying the Resistance to Prion Diseases - Softcover

Inhaltsangabe

1. Basic Knowledge

Part I Molecular Dynamics of Prion Proteins

2. The Homology Structure and Dynamics
3. The NMR Structure and Dynamics of the Wild-type and Mutants
4. Compared with the NMR Structure and Dynamics of Humans and Mice
5. Compared with the NMR Structure and Dynamics of Dogs and Horses
6. Compared with a Homology Structure and Dynamics of Buffaloes
7. Compared with NMR Structure and Dynamics of Elks
8. Compared with the X-ray Structure and Dynamics of Rabbits
9. Surface Electrostatic Charge Distributions
10. The Hydrophobic Region PrP(109-136)

Part II Molecular Modeling of Prions

11. The Hybrid Method of Steepest Descent - Conjugate Gradient with Simulated Annealing
12. Hybrid Method of Discrete Gradient with Simulated Annealing or Genetic Algorithm
13. A Novel Canonical Dual Global Optimization Computational Approach
14. The Hybrid Method of Evolutionary Computations with Simulated Annealing
15. Simulated Annealing Refined Replica Exchange Global Search Algorithm
16. LBFGS Quasi-Newtonian Methods for MM Prion AGAAAAGA Amyloid Fibrils
17. Particle Swarm Global Optimization Search Algorithm
18. A Summary of the Research Works on AGAAAAGA

References

Index

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