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DNA Alterations in Lynch Syndrome: Advances in Molecular Diagnosis and Genetic Counselling - Hardcover
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Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients.
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Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients. This book provides an up-to-date overview on the genetic and epigenetic basis of Lynch syndrome. It evaluates clinical features of the disease and critically comments on molecular tools available for identifying mutations responsible for Lynch syndrome; in addition the importance of functional assays that can help clarify the clinical nature of identified mutations is also discussed. The book also focuses on challenges in genetic counselling of at-risk individuals and discusses related ethical issues. The purpose of the book is to give a concise knowledge base for the broader scientific and medical community, including genetic counselors, in order to improve awareness on the potential impact that the diagnosis of LS has on treatment, management and surveillance of LS patients.
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DNA Alterations in Lynch Syndrome: Advances in molecular diagnosis and genetic counselling
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DNA Alterations in Lynch Syndrome : Advances in molecular diagnosis and genetic counselling
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DNA Alterations in Lynch Syndrome : Advances in molecular diagnosis and genetic counselling
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DNA Alterations in Lynch Syndrome
Verlag:
Springer Netherlands, Springer Netherlands Mai 2013, 2013
ISBN 10: 9400765967
ISBN 13: 9789400765962
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Buch. Zustand: Neu. Neuware -Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients. This book provides an up-to-date overview on the genetic and epigenetic basis of Lynch syndrome. It evaluates clinical features of the disease and critically comments on molecular tools available for identifying mutations responsible for Lynch syndrome; in addition the importance of functional assays that can help clarify the clinical nature of identified mutations is also discussed. The book also focuses on challenges in genetic counselling of at-risk individuals and discusses related ethical issues. The purpose of the book is to give a concise knowledge base for the broader scientific and medical community, including genetic counselors, in order to improve awareness on the potential impact that the diagnosis of LS has on treatment, management and surveillance of LS patients.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 208 pp. Englisch. Artikel-Nr. 9789400765962
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DNA Alterations in Lynch Syndrome: Advances in Molecular Diagnosis and Genetic Counselling
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Hardcover. Zustand: Brand New. 1st edition. 195 pages. 9.50x6.50x0.75 inches. In Stock. Artikel-Nr. x-9400765967
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DNA Alterations in Lynch Syndrome : Advances in molecular diagnosis and genetic counselling
Verlag:
Springer Netherlands, Springer Netherlands, 2013
ISBN 10: 9400765967
ISBN 13: 9789400765962
Neu
Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients. This book provides an up-to-date overview on the genetic and epigenetic basis of Lynch syndrome. It evaluates clinical features of the disease and critically comments on molecular tools available for identifying mutations responsible for Lynch syndrome; in addition the importance of functional assays that can help clarify the clinical nature of identified mutations is also discussed. The book also focuses on challenges in genetic counselling of at-risk individuals and discusses related ethical issues. The purpose of the book is to give a concise knowledge base for the broader scientific and medical community, including genetic counselors, in order to improve awareness on the potential impact that the diagnosis of LS has on treatment, management and surveillance of LS patients. Artikel-Nr. 9789400765962
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