Inhaltsangabe
Cancer genetics is a field of daunting breadth and depth. The literature describes hundreds of genes and genetic alterations that are variably associated with again as many disease states and risk factors. Integrating these disparate pieces of highly specialized information is challenging for the professional scientist and student alike. This concise guidebook consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. The book is focused on the most highly representative genes that underlie the most common cancers and highlights new frontiers in gene-based diagnosis and therapy. Primary attention is devoted to the origins of cancer genes and the application of evolutionary theory to explain why the cell clones that harbor cancer genes tend to expand.
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Fred Bunz, M.D., Ph.D is a research scientist, lecturer and author at the Johns Hopkins School of Medicine. A native of Long Beach, New York, Dr. Bunz attended Stony Brook University and received training in cancer genetics at Cold Spring Harbor Laboratory and Johns Hopkins University, which he joined as a fellow of the Howard Hughes Medical Institute. Dr. Bunz currently heads a laboratory at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins that investigates the effects of DNA damage and pathogens on cancer cells and normal cells. He lives in Baltimore with his family.
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Principles of Cancer Genetics
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Taschenbuch. Zustand: Neu. Principles of Cancer Genetics | Fred Bunz | Taschenbuch | xii | Englisch | 2010 | Springer | EAN 9789048177264 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Artikel-Nr. 107219320
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Principles of Cancer Genetics
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Springer Netherlands, Springer Netherlands, 2010
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Cancer genetics is a field of daunting breadth and depth. The literature describes hundreds of genes and genetic alterations that are variably associated with again as many disease states and risk factors. Integrating these disparate pieces of highly specialized information is challenging for the professional scientist and student alike. Prinicples of Cancer Genetics consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer.Focused on the most highly representative genes that underlie the most common cancers, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory courses in genetics, biology and biochemistry, medical students, and house medical house staff preparing for board examinations. Primary attention is devoted to the origins of cancer genes and the application of evolutionary theory to explain why the cell clones that harbor cancer genes tend to expand. The many points of controversy in cancer research are avoided, in favor of firmly established concepts. This book does not delve into tumor pathobiology beyond what is required to understand the role of genetic alterations in neoplastic growth. For students with a general interest in cancer, this book will provide a highly accessible overview. For students contemplating future study in the fields of oncology or cancer research, this book will be useful as a primer. Artikel-Nr. 9789048177264
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