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Hardcover. Zustand: As New. Dust Jacket Included. Contents Preface. 1. The influence of environmental factors on the action of mutant genes/Werner Gottschalk. 2. Genome organization in plant cells is repetitive DNA redundant/V.K. Shumny and A.V. Vershinin. 3. Human and animal hepatocyte xenobiotic metabolism/Kenneth Rudo and Robert Langenbach. 4. Recent developments in the cellular genetics of the skin/E. Maxwell Nicholls. 5. Monitoring human exposure to carcinogens by DNA adduct measurement/Regina M. Santella. 6. Use of cytogenetics in detection of human exposure to mutagens and carcinogens in the workplace/Marja Sorsa. 7. Genetic architecture of chromosome/Arun Kuar Sharma. 8. Some botanical consequences of tectonics and orogeny/R.O. Whyte. 9. Metals as clastogens some aspects of study/Archana Sharma and Geeta Talukder. Author index. This book covers advances in other areas of chromosome study as far as practicable. The clarification of organizational elements of chromosomes has led to a deep understanding of chromosome skeleton. The genome organization in the plant system in which so called redundant sequences form inherent components still provides challenging problems. The extent to which environment affects the mutant genes which themselves yield variability is of special interest. Chromosome study in plants in relation to antiquity and geological events is extremely fascinating. In the area of human genetics and genetic toxicology the clastogenicity of the metals their synergistic and antagonistic properties drug toxicity and occupational mutagenicity and carcinogenicity have led to a deeper understanding of environmental problems. The study on xenobiosis has helped in correlating metabolism and carinogenesis. The continued addition of test systems and DNA adducts in genotixicity assay are yielding valuable data. Research on skin genetics is an important facet of medical genetics. An attempt has been made to present the advances in all these areas of chromosome research which are of special value in biology medicine and agriculture. (jacket) 230 pp. Artikel-Nr. 100002189
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