IDENTIFICATION AND CHARACTERIZATION OF NOVEL NATURAL NF-κB INHIBITORS: A MOLECULAR DOCKING STUDY - Softcover

Inhaltsangabe

Nuclear factor-κB (NF-κB) depict a family of transcription factors, which modulate collection of genes associated with inflammatory and immune responses. Inevitable NF-κB activation involve pathogenic process of various diseases like inflammation and cancer. NF-κB signaling in cancer cells is involved in cellular proliferation, angiogenesis, invasion, metastasis, development of drug resistance and anti-apoptosis. The present study was aimed to identify potent NF-kB inhibitors using molecular docking study.

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