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PULSATILE DRUG DELIVERY SYSTEMS IN CHRONOTHERAPY: Formulation and Evaluation of Compression-Coated Tablets for Chronotherapeutic Management of Nocturnal Asthma - Softcover

Kulkarni, Gururaj S.; Joseph, Lis Maria; Kishor, Hari

 
9786207478613: PULSATILE DRUG DELIVERY SYSTEMS IN CHRONOTHERAPY: Formulation and Evaluation of Compression-Coated Tablets for Chronotherapeutic Management of Nocturnal Asthma

Inhaltsangabe

Chronopharmaceutical drug delivery represents a progressive shift in pharmaceutical research, emphasizing the synchronization of drug release with the body's biological rhythms to maximize therapeutic efficacy and minimize adverse effects. This book provides a comprehensive and systematic account of pulsatile drug delivery systems as an advanced oral drug delivery approach designed to meet the time-dependent needs of circadian rhythm-related diseases.The text elaborates on the fundamental principles of chronotherapy and pulsatile drug delivery, detailing their classification, design strategies, mechanisms of drug release, and technological advancements. Special emphasis is placed on time-controlled, site-specific, and stimuli-responsive pulsatile systems, with in-depth discussion of tablet-based, capsule-based, and multiparticulate delivery platforms. The role of polymer science and formulation variables in controlling lag time and release kinetics is thoroughly examined.

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Über die Autorin bzw. den Autor

Dr Gururaj S. Kulkarni is a professor and Head of the Department of Pharmaceutics at the Oxford College of Pharmacy, Bengaluru, with over a decade of experience in academics and research focusing on pharmaceutics, formulation development and novel drug delivery approaches.

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