Quantification of DNA and AgNORs: correlating to cyclin D1-immunoexpression in human breast cancer - Softcover

Assem Hamed, Mahmoud

 
9786204725413: Quantification of DNA and AgNORs: correlating to cyclin D1-immunoexpression in human breast cancer
Softcover
ISBN 10: 6204725416 ISBN 13: 9786204725413
Verlag: LAP LAMBERT Academic Publishing, 2021

Inhaltsangabe

Assessment of cell proliferation through the evaluation of cyclin D1, AgNORs, and DNA content provides a promising approach to the prognosis of breast cancer. Therefore, this work aimed to evaluate the prognostic significance of AgNORs and DNA image cytometry, and their relation to cyclin D1 immunoreactivity in breast cancer. This study was carried out on 50 prospective biopsies taken from patients with breast tumor. They were divided into control (10 cases) and benign (10 cases) as well as malignant (30 cases) groups. Computer-assisted image analysis cytometry is applied to evaluate the count of positive reactions of AgNORs and cyclin D1, and an integrated optical density (IOD) technique is used to quantify DNA content in the tissues stained by Feulgen stain and to assess the density of cyclin D1 immunoreactivity.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2021
Sprache
Englisch
ISBN 10 
6204725416
ISBN 13 
9786204725413
Einband
Tapa blanda
Anzahl der Seiten
52
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