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Development and validation of simple, precise, accurate, economical and sensitive HPLC assay method for the estimation of Cefixime and Linezolid in tablet dosage form. A chromatographic separation was achieved with a Hypersil BDS C18 (250mm,4.6mm ,5µm) analytical column. A Mixture of Phosphate Buffer (3.0 pH): methanol (40:60, v/v) was used as the mobile phase, at a flow rate of 1.0 ml/min and detector wavelength at 277 nm. The retention time of Cefixime and linezolid was found to be 3.76 and 6.55 min respectively. Theoretical plates was 6896 and 4626 respectively and Tailing factor was 1.32 and 1.28. The linear ranges was 5-15 for cefixime and 15-45 μg/ml for linezolid, and the correlation coefficient was 0.999 for both drugs. The relative standard deviation was found to be less than 2%. A simple, precise, accurate, economical and sensitive HPLC assay method have been developed and validated for the estimation of Cefixime and linezolid in tablet dosage form. All method validation parameters lie within its acceptance crieteria as per ICH Q2(R1) guideline.
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Simultaneous Estimation of Cefixime and Linezolid : By HPLC Method
Verlag:
LAP LAMBERT Academic Publishing, 2019
ISBN 10: 6139454751
ISBN 13: 9786139454754
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Softcover
Anbieter: Buchpark, Trebbin, Deutschland
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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher. Artikel-Nr. 34027967/2
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Beispielbild für diese ISBN
Simultaneous Estimation of Cefixime and Linezolid : By HPLC Method
Verlag:
LAP LAMBERT Academic Publishing, 2019
ISBN 10: 6139454751
ISBN 13: 9786139454754
Gebraucht
Softcover
Anbieter: Buchpark, Trebbin, Deutschland
Verkäuferbewertung 5 von 5 Sternen
Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher. Artikel-Nr. 34027967/1
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Simultaneous Estimation of Cefixime and Linezolid
Verlag:
LAP LAMBERT Academic Publishing Feb 2019, 2019
ISBN 10: 6139454751
ISBN 13: 9786139454754
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Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland
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Taschenbuch. Zustand: Neu. Neuware -Development and validation of simple, precise, accurate, economical and sensitive HPLC assay method for the estimation of Cefixime and Linezolid in tablet dosage form. A chromatographic separation was achieved with a Hypersil BDS C18 (250mm,4.6mm ,5µm) analytical column. A Mixture of Phosphate Buffer (3.0 pH): methanol (40:60, v/v) was used as the mobile phase, at a flow rate of 1.0 ml/min and detector wavelength at 277 nm. The retention time of Cefixime and linezolid was found to be 3.76 and 6.55 min respectively. Theoretical plates was 6896 and 4626 respectively and Tailing factor was 1.32 and 1.28. The linear ranges was 5-15 for cefixime and 15-45 ¿g/ml for linezolid, and the correlation coefficient was 0.999 for both drugs. The relative standard deviation was found to be less than 2%. A simple, precise, accurate, economical and sensitive HPLC assay method have been developed and validated for the estimation of Cefixime and linezolid in tablet dosage form. All method validation parameters lie within its acceptance crieteria as per ICH Q2(R1) guideline.Books on Demand GmbH, Überseering 33, 22297 Hamburg 88 pp. Englisch. Artikel-Nr. 9786139454754
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