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Rule of Three (Medicine): Statistical Analysis, Clinical Trials, Adverse Event, Confidence (Statistics), Pharmaceutical, Pain Relief - Softcover
Inhaltsangabe
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In the statistical analysis of clinical trials, the rule of three states that if no major adverse events occurred in a group of n people, there can be 95% confidence that the chance of major adverse events is less than one in n / 3 (or equivalently, less than 3 in n). This is an approximate result, but is a very good approximation when n > 30. For example, in a trial of a drug for pain relief in 1500 people, none have a major adverse event. The rule of three says we should have 95% confidence that the rate of adverse events is no more frequent than 1 in 500.
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Reseña del editor
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In the statistical analysis of clinical trials, the rule of three states that if no major adverse events occurred in a group of n people, there can be 95% confidence that the chance of major adverse events is less than one in n / 3 (or equivalently, less than 3 in n). This is an approximate result, but is a very good approximation when n > 30. For example, in a trial of a drug for pain relief in 1500 people, none have a major adverse event. The rule of three says we should have 95% confidence that the rate of adverse events is no more frequent than 1 in 500.
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