Systemic Sclerosis: Basic and Translational Research - Hardcover

 
9784431557074: Systemic Sclerosis: Basic and Translational Research

Inhaltsangabe

This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma). Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.

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Über die Autorin bzw. den Autor

Dr. Kazuhiko Takehara
Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan

Dr. Manabu Fujimoto
Department of Dermatology, University of Tsukuba, Japan

Dr. Masataka Kuwana
Department of Allergy and Rheumatology, Nippon Medical School, Japan

Von der hinteren Coverseite

​This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma). Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.

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Weitere beliebte Ausgaben desselben Titels

9784431566809: Systemic Sclerosis

Vorgestellte Ausgabe

ISBN 10:  4431566805 ISBN 13:  9784431566809
Verlag: Springer, 2018
Softcover