Interface Between Chemistry and Biochemistry: v. 73 (Experientia Supplementum) - Hardcover

9783764350819: Interface Between Chemistry and Biochemistry: v. 73 (Experientia Supplementum)

Hardcover

ISBN 10: 3764350814 ISBN 13: 9783764350819

Verlag: Birkhauser Verlag AG, 1995

The developing importance of the interface between chemistry and biology is probably the largest change to have occurred in chemistry in the past 15 years. Increasingly more chemists work on problems dealing with biology, and interfacial research is poised to move into the main- stream of both disciplines. This merging of two types of approach has resulted in a vigorous research discipline with unprecedented potential to address important biological and chemical problems. A series of exam- ples is developed in this book. Analytical aspects are discussed in several chapters. Fundamental concepts do not only derive from chemistry, but chemistry has provided biochemistry with powerful tools of analysis. Equally important, phys- icochemical methods allow studies of nucleic acids and lipids, lipases, receptors and other membrane proteins. Several chapters deal with enzymes in different contexts. The part devoted to metalloproteins is directed toward zinc metallochemistry and NMR structural work on zinc proteins. Chemists have been able to bring to biology their characteristic approach of synthesizing new molecules. These aspects are treated in chapters devoted to glycopeptides and uses of peptides as probes. Further fields of interest in combining different disciplines concern novel active compounds, such as surfactant peptides and catalytic antibodies in studies resulting from close collaboration between chemists and bio- chemists.

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Rese�a del editor

The developing importance of the interface between chemistry and biology is probably the largest change to have occurred in chemistry in the past 15 years. Increasingly more chemists work on problems dealing with biology, and interfacial research is poised to move into the main� stream of both disciplines. This merging of two types of approach has resulted in a vigorous research discipline with unprecedented potential to address important biological and chemical problems. A series of exam� ples is developed in this book. Analytical aspects are discussed in several chapters. Fundamental concepts do not only derive from chemistry, but chemistry has provided biochemistry with powerful tools of analysis. Equally important, phys� icochemical methods allow studies of nucleic acids and lipids, lipases, receptors and other membrane proteins. Several chapters deal with enzymes in different contexts. The part devoted to metalloproteins is directed toward zinc metallochemistry and NMR structural work on zinc proteins. Chemists have been able to bring to biology their characteristic approach of synthesizing new molecules. These aspects are treated in chapters devoted to glycopeptides and uses of peptides as probes. Further fields of interest in combining different disciplines concern novel active compounds, such as surfactant peptides and catalytic antibodies in studies resulting from close collaboration between chemists and bio� chemists.

Rese�a del editor

The increasing importance of the interface between chemistry and biology is probably the largest change in chemistry in the past 15 years. More and more organic chemists are working on problems dealing with biology. Once considered to be at the very outside edge of either field, interfacial research is poised to move into the mainstream of both disciplines. This merging of two types of approach has resulted in a vigorous research discipline with unprecedented potential to address important biological and chemical problems. A series of examples are developed in this book. Some analytical aspects are discussed first as the fundamental concepts are not only chemical, but chemistry has provided biochemistry with powerful tools of analysis. Physico-chemical aspects are devoted to spectrometric studies of nucleic acids as well as lipids, lipases and membrane proteins (receptors). Three chapters are included in the section dealing with enzymes. The part devoted to metalloproteins is mainly directed toward zinc metallochemistry and NMR structural work on zinc proteins. Chemists have been able to bring to biology their characteristic approach of synthesizing new molecules; three chapters are devoted to peptides, sugar compounds and biocatalysts. Two chapters discuss new active compounds (antibacterial peptides, catalytic antibodies), which are the result of collaboration between chemists and biochemists.

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