Within the dynamic and ever-evolving landscape of manufacturing systems and industrial engineering, an unparalleled synergy has emerged-one that wields the power to redefine the boundaries of innovation and optimization. At the heart of this transformative confluence lies the seamless integration of simulation, modeling, and decision-making processes, collectively constituting a driving force that propels the industrial world toward unprecedented efficiency, resilience, and sustainability. In this era of relentless technological advancement, characterized by the rapid emergence of Industry 4.0, smart factories, and the relentless pursuit of excellence in industrial processes, the marriage of simulation, modeling, and decision-making has taken center stage. These intertwined disciplines not only illuminate the path toward innovation, but also serve as indispensable tools for understanding, optimizing, and reimagining the complex fabric of manufacturing systems and industrial engineering. This Special Issue delves into the heart of contemporary manufacturing and industrial engineering, where simulation techniques, advanced modeling approaches, and astute decision-making strategies converge to address the multifaceted challenges of our times.
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