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Simultaneous estimation of Atorvastatin, Clopidogril & Aspirin: Simultaneous estimation of Atorvastatin, Clopidogril and Aspirin by using UV-VIZ Spectroscopy - Softcover
Inhaltsangabe
Atorvastatin [R-(R*,R*)]-2-(4-fluorophenyl)-ß, -dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenyl amino)carbonyl]-1H-pyrrole 1-heptanoic acid an Anti-hyperlipidemia and Clopidogrel (2-Chloro phenyl, 6-7 dihydro4H thieno [3,2-c]pyridine-5-yl)acetic acid is an Anti-platelet drug and Aspirin (2-Acetoxy benzoic acid) an NSAIDs. This paper presents two methods i.e. first derivative spectrophotometery and multicomponent spectrophotometery for simultaneous estimation of these three drugs combination in pharmaceutical formulations. The first derivative amplitudes at 276, 226 and 222 nm were utilized for simultaneous estimations. The multicomponent amplitudes at 247, 220 and 235 nm were utilizatied. Proper selection of wavelength for estimations of one drug by other in derivative spectra and multicomponent lead to successful development of methods for simultaneous estimation. The results of analysis were validated statistically that included parameters such as precision, LOD, LOQ, recovery and robustness. Both methods were simple, economical, accurate, reproducible and precise.
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Reseña del editor
Atorvastatin [R-(R*,R*)]-2-(4-fluorophenyl)-ß, -dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenyl amino)carbonyl]-1H-pyrrole 1-heptanoic acid an Anti-hyperlipidemia and Clopidogrel (2-Chloro phenyl, 6-7 dihydro4H thieno [3,2-c]pyridine-5-yl)acetic acid is an Anti-platelet drug and Aspirin (2-Acetoxy benzoic acid) an NSAIDs. This paper presents two methods i.e. first derivative spectrophotometery and multicomponent spectrophotometery for simultaneous estimation of these three drugs combination in pharmaceutical formulations. The first derivative amplitudes at 276, 226 and 222 nm were utilized for simultaneous estimations. The multicomponent amplitudes at 247, 220 and 235 nm were utilizatied. Proper selection of wavelength for estimations of one drug by other in derivative spectra and multicomponent lead to successful development of methods for simultaneous estimation. The results of analysis were validated statistically that included parameters such as precision, LOD, LOQ, recovery and robustness. Both methods were simple, economical, accurate, reproducible and precise.
Biografía del autor
(Dr.) Sunil Singh is working as Asociate Progessor in Oriental College of Pharmacy, Bhopal, he is having more than 8 years teaching experiences, he has published more then 50 national and international research papers and presented abstracts in different national and international conferences.
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Simultaneous estimation of Atorvastatin, Clopidogril & Aspirin
Verlag:
LAP Lambert Academic Publishing Sep 2016, 2016
ISBN 10: 3659942812
ISBN 13: 9783659942815
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Taschenbuch
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Taschenbuch. Zustand: Neu. Neuware -Atorvastatin [R-(R\*,R\*)]-2-(4-fluorophenyl)-ß, -dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenyl amino)carbonyl]-1H-pyrrole 1-heptanoic acid an Anti-hyperlipidemia and Clopidogrel (2-Chloro phenyl, 6-7 dihydro4H thieno [3,2-c]pyridine-5-yl)acetic acid is an Anti-platelet drug and Aspirin (2-Acetoxy benzoic acid) an NSAIDs. This paper presents two methods i.e. first derivative spectrophotometery and multicomponent spectrophotometery for simultaneous estimation of these three drugs combination in pharmaceutical formulations. The first derivative amplitudes at 276, 226 and 222 nm were utilized for simultaneous estimations. The multicomponent amplitudes at 247, 220 and 235 nm were utilizatied. Proper selection of wavelength for estimations of one drug by other in derivative spectra and multicomponent lead to successful development of methods for simultaneous estimation. The results of analysis were validated statistically that included parameters such as precision, LOD, LOQ, recovery and robustness. Both methods were simple, economical, accurate, reproducible and precise.Books on Demand GmbH, Überseering 33, 22297 Hamburg 88 pp. Englisch. Artikel-Nr. 9783659942815
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Simultaneous estimation of Atorvastatin, Clopidogril & Aspirin: Simultaneous estimation of Atorvastatin, Clopidogril and Aspirin by using UV-VIZ Spectroscopy
Verlag:
LAP LAMBERT Academic Publishing, 2016
ISBN 10: 3659942812
ISBN 13: 9783659942815
Neu
Paperback
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Paperback. Zustand: Brand New. 88 pages. 8.66x5.91x0.20 inches. In Stock. Artikel-Nr. 3659942812
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