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Formulation And Evaluation of Metformin and Glimepiride: Sustained Release Metformin And Immidiate Release Glimepiride - Softcover
Inhaltsangabe
The objective of this research was to develop a combined anti-diabetic formulation of two different drugs acting by different mechanism. So they can complement each other and together lower the blood glucose level effectively. Metformin and glimepiride act by different mechanisms. Glimepiride reduce hyper glycaemia by enhancing insulin secretion, whereas metformin acts to improve insulin sensitivity and suppress hepatic glucose output. Because of their complementary mechanism of action, combination therapy with glimepiride and metformin would be rational and may lead to benefits in terms of improved glycaemic control and improved tolerability at lower doses of the individual agents.Sustained drug delivery can improve patient compliance and help in maintaining effective level of blood glucose.
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Über die Autorin bzw. den Autor
Anil Kumar Sahdev*( Assistant Professor) and Khushboo Gupta (M.Pharma), Innovative college of pharmacy Greater noida (Uttar Pradesh), India.
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Formulation And Evaluation of Metformin and Glimepiride
Verlag:
LAP LAMBERT Academic Publishing Apr 2017, 2017
ISBN 10: 3659781312
ISBN 13: 9783659781315
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Taschenbuch. Zustand: Neu. Neuware -The objective of this research was to develop a combined anti-diabetic formulation of two different drugs acting by different mechanism. So they can complement each other and together lower the blood glucose level effectively. Metformin and glimepiride act by different mechanisms. Glimepiride reduce hyper glycaemia by enhancing insulin secretion, whereas metformin acts to improve insulin sensitivity and suppress hepatic glucose output. Because of their complementary mechanism of action, combination therapy with glimepiride and metformin would be rational and may lead to benefits in terms of improved glycaemic control and improved tolerability at lower doses of the individual agents.Sustained drug delivery can improve patient compliance and help in maintaining effective level of blood glucose.Books on Demand GmbH, Überseering 33, 22297 Hamburg 84 pp. Englisch. Artikel-Nr. 9783659781315
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Formulation And Evaluation of Metformin and Glimepiride: Sustained Release Metformin And Immidiate Release Glimepiride
Verlag:
LAP LAMBERT Academic Publishing, 2017
ISBN 10: 3659781312
ISBN 13: 9783659781315
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Paperback. Zustand: Brand New. 84 pages. 8.66x5.91x0.19 inches. In Stock. Artikel-Nr. 3659781312
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