Bone Mineral Density and Body Composition: Bone mineral density and body composition in children and adolescents with celiac disease and inflammatory bowel disease - Softcover
Inhaltsangabe
Chronic gastrointestinal diseases, such as celiac disease and inflammatory bowel disease (IBD), cause changes in bone metabolism. They impair bone mineralization and can also alter bone mineral density (BMD). Low BMD is a risk factor for osteoporosis and bone fracture, not only in later years, but also in childhood and adolescence. In our study we compared BMD, bone age and vitamin D levels within different groups of children. We also measured body composition and evaluated usefulness of bioelectrical impedance analysis (BIA) in predicting low BMD. Serologic markers EMA and t-TG were measured to determine the compliance with gluten-free diet. The results of the study show significant decrease in serum vitamin D levels in patients with celiac disease and IBD compared to the control group. Body composition, measured with BIA did not correlate with BMD so we cannot confirm the value of this method in diagnosis of low BMD. However, the correlation between BMD and t-TG values in celiac patients was confirmed. Therefore, the importance of strict gluten-free diet is emphasized.
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Reseña del editor
Chronic gastrointestinal diseases, such as celiac disease and inflammatory bowel disease (IBD), cause changes in bone metabolism. They impair bone mineralization and can also alter bone mineral density (BMD). Low BMD is a risk factor for osteoporosis and bone fracture, not only in later years, but also in childhood and adolescence. In our study we compared BMD, bone age and vitamin D levels within different groups of children. We also measured body composition and evaluated usefulness of bioelectrical impedance analysis (BIA) in predicting low BMD. Serologic markers EMA and t-TG were measured to determine the compliance with gluten-free diet. The results of the study show significant decrease in serum vitamin D levels in patients with celiac disease and IBD compared to the control group. Body composition, measured with BIA did not correlate with BMD so we cannot confirm the value of this method in diagnosis of low BMD. However, the correlation between BMD and t-TG values in celiac patients was confirmed. Therefore, the importance of strict gluten-free diet is emphasized.
Biografía del autor
Author Zan Ferant graduated General medicine at Medical faculty, University of Maribor, Slovenia. His research interest is focused on pediatrics, especially growth and development of children in chronic diseases.
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Bone Mineral Density and Body Composition
Verlag:
LAP LAMBERT Academic Publishing Aug 2014, 2014
ISBN 10: 3659584991
ISBN 13: 9783659584992
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Taschenbuch. Zustand: Neu. Neuware -Chronic gastrointestinal diseases, such as celiac disease and inflammatory bowel disease (IBD), cause changes in bone metabolism. They impair bone mineralization and can also alter bone mineral density (BMD). Low BMD is a risk factor for osteoporosis and bone fracture, not only in later years, but also in childhood and adolescence. In our study we compared BMD, bone age and vitamin D levels within different groups of children. We also measured body composition and evaluated usefulness of bioelectrical impedance analysis (BIA) in predicting low BMD. Serologic markers EMA and t-TG were measured to determine the compliance with gluten-free diet. The results of the study show significant decrease in serum vitamin D levels in patients with celiac disease and IBD compared to the control group. Body composition, measured with BIA did not correlate with BMD so we cannot confirm the value of this method in diagnosis of low BMD. However, the correlation between BMD and t-TG values in celiac patients was confirmed. Therefore, the importance of strict gluten-free diet is emphasized.Books on Demand GmbH, Überseering 33, 22297 Hamburg 60 pp. Englisch. Artikel-Nr. 9783659584992
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