Washout Rate of Tc-99m Mibi in Bone and Soft-Tissue Sarcomas: Is it a predictor of Tissue Necrosis caused by Neoadjuvant Therapy? - Softcover

Sohaib Muhammad

 
9783659580505: Washout Rate of Tc-99m Mibi in Bone and Soft-Tissue Sarcomas: Is it a predictor of Tissue Necrosis caused by Neoadjuvant Therapy?
Softcover
ISBN 10: 3659580503 ISBN 13: 9783659580505
Verlag: LAP Lambert Academic Publishing, 2014

Inhaltsangabe

Neoadjuvant therapy is employed before the primary treatment of sarcomas. It is not uncommon that it fails due to multi-drug resistance gene causing unnecessary delays in surgery. Tc-99m MIBI, a radiopharmaceutical, is taken-up in these tumours. Being substrate of P-glycoprotein (Pgp), its washout from the malignant tissue may predict the response of sarcoma to neoadjuvant therapy. This book presents the author's experience of in-vivo quantitative estimation of the washout rates of Tc-99m MIBI from nuclear medicine scans of various bone and soft-tissue sarcomas. These rates were then assessed for their ability to predict the effectiveness of neoadjuvant therapy initiated afterwards.

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Über die Autorin bzw. den Autor

Dr Muhammad Sohaib is a nuclear medicine physician with medical graduation from Quaid-e-Azam Medical College, masters from PIEAS and clinical fellowship from CPSP. Currently he is a faculty member in PIEAS working as an academician, researcher and clinician. He has several research articles to his credit published in high impact factor journals.

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Verlag
LAP Lambert Academic Publishing
Erscheinungsdatum
2014
Sprache
Englisch
ISBN 10 
3659580503
ISBN 13 
9783659580505
Einband
Tapa blanda
Anzahl der Seiten
80
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