Diosgenin: Diosgenin against Chemical Induced Mammary Carcinogenesis and In MCF-7 Human Breast Cancer Cell Line

 
9783659156618: Diosgenin: Diosgenin against Chemical Induced Mammary Carcinogenesis and In MCF-7 Human Breast Cancer Cell Line

Breast cancer is one of the second most common cancers in the world. Recent research suggest that plant derived drugs are of great interest due to its health benefits not only food substances of plant origin but also for the therapeutic usage to combat against various ailments due to the absence of adverse side effects. In the present investigation, efficacy of diosgenin in mammary carcinoma cell line (MCF-7) and in experimental breast cancer was investigated. Inhibition of MCF-7 cells is likely to be selective apoptotic nature of the compound diosgenin. In addition, diosgenin is very effective in preventing chemical induced breast cancer possibly through antioxidant and antigenotoxic nature, which was confirmed by various biochemical and molecular events.Thus,the anticancer properties of diosgenin could be useful information for the possible application in cancer prevention and cancer therapy.

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About the Author:

Jagadeesan Jayaraman completed his PG in Bio Medical Genetics and received doctoral degree from the department of Pharmacology and ET, University of Madras,India.Dr.K.Langeswaran,Asst Prof,Bharath University has co-authored many books/ Journals to his credit.Dr.S.Gowtham Kumar,Asst Prof,Chettinad University has co-authored many books to his credit.

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