DNA replication is a key event in the cell cycle. Although our knowledge is far from complete and many elusive regulatory mechanisms still remain beyondour grasp, many enzymes and a multiplicity of biochemical mechanisms involved have been discovered. Recent findings in E. coli have confirmed and yet surpassed the original hypothesis of F. Jacob. In yeast and higher eucaryotes, the apparent redundancy in putative origins and initiators has made an estimation of the importance of each identified element difficult to access. In spite of well established methodologies - which are also described in the book - the origin identification in mammalian chromosomes is still a controversial subject. On the other hand, considerable advances have been made in our understanding of virus DNA replication and this continues to deepen and broaden our understanding of the controls of cellular DNA replication.
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Taschenbuch. Zustand: Neu. DNA Replication: The Regulatory Mechanisms | Patrick Hughes (u. a.) | Taschenbuch | xx | Englisch | 2011 | Springer Vieweg | EAN 9783642769900 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Artikel-Nr. 106368693
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - DNA replication is a key event in the cell cycle. Althoughour knowledge is far from complete and many elusiveregulatory mechanisms still remain beyondour grasp, manyenzymes and a multiplicity of biochemical mechanismsinvolved have been discovered. Recent findings in E. colihave confirmed and yet surpassed the original hypothesis ofF. Jacob. In yeast and higher eucaryotes, the apparentredundancy in putative origins and initiators has made anestimation of the importance of each identified elementdifficult to access. In spite of well establishedmethodologies - which are also described in the book - theorigin identification in mammalian chromosomes is still acontroversial subject. On the other hand, considerableadvances have been made in our understanding of virus DNAreplication and this continues to deepen and broaden ourunderstanding of the controls of cellular DNA replication. Artikel-Nr. 9783642769900
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