RNP Particles, Splicing and Autoimmune Diseases (Springer Lab Manuals) - Softcover

 
9783642489754: RNP Particles, Splicing and Autoimmune Diseases (Springer Lab Manuals)
Softcover
ISBN 10: 3642489753 ISBN 13: 9783642489754
Verlag: Springer, 2012

Inhaltsangabe

Information stored in DNA needs to be translated into functional proteins. Ribonucleoprotein (RNP) particles play a major role in this process. In many autoimmune diseases, antibodies are directed against components of these particles. Detailed protocols for analysing the structure and function of RNPs are described in this manual.

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The maturation of the precursors of mRNA to a functional transcript in eukaryotic cells is a complex, multistep process. It includes the formation of RNP complexes and the splicing procedure. Also, the presence of snRNA packaged as snRNP particles plays an important role in this process. In addition, snRNPs are involved in various autoimmune diseases in which autoantibodies are directed against components of these particles.
Relevant techniques to investigate RNA processing, splicing, protein-RNA complex formation and protein-RNA interactions as well as the use of autoantibodies in basic and clinical research are presented in this manual.

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Verlag
Springer
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3642489753
ISBN 13 
9783642489754
Einband
Taschenbuch
Anzahl der Seiten
236
Herausgeber
Schenkel Johannes
Kontakt zum Hersteller
ProductSafety@springernature.com
ProductSafety@springernature.com

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Darmstadt
64293
Deutschland

Weitere beliebte Ausgaben desselben Titels

9783540624486: RNP Particles, Splicing and Autoimmune Diseases (Springer Lab Manual)

Vorgestellte Ausgabe

ISBN 10:  3540624481 ISBN 13:  9783540624486
Verlag: Springer, 1998
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