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Theory and Mathematical Methods in Bioinformatics (Biological and Medical Physics, Biomedical Engineering) - Hardcover

 
9783540748908: Theory and Mathematical Methods in Bioinformatics (Biological and Medical Physics, Biomedical Engineering)

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Book by Shen Shiyi

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This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. Prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed.

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This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. The book will be useful to students, research scientists and practitioners of bioinformatics and related fields, especially those who are interested in the underlying mathematical methods and theory. Among the methods presented in the book, prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed. In particular, for proteins an in-depth exposition of secondary structure prediction methods should be a valuable tool in both molecular biology and in applications to rational drug design. The book can also be used as a textbook and for this reason most of the chapters include exercises and problems at the level of a graduate program in bioinformatics.

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  • VerlagSpringer
  • Erscheinungsdatum2008
  • ISBN 10 3540748903
  • ISBN 13 9783540748908
  • EinbandTapa dura
  • SpracheEnglisch
  • Anzahl der Seiten464

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Shen, Shiyi
Verlag: Springer, 2008
ISBN 10: 3540748903 ISBN 13: 9783540748908
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Shiyi Shen
ISBN 10: 3540748903 ISBN 13: 9783540748908
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Bioinformatics is an interdisciplinary science which involves molecular bi- ogy, molecular chemistry, physics, mathematics, computational sciences, etc. Mostofth Elektronisches Buchonbiomathematicspublishedwithinthepasttenyearshave consistedofcollectionsofstandardbioinformaticsproblemsandinformational methods,andfocus mainly onthe logisticsofimplementing andmakinguse of various websites, databases, software packages and serving platforms. While these types of books do introduce some mathematical and computational methods alongside the software packages, they are lacking in a systematic and professional treatment of the mathematics behind these methods. It is signi cant in the eld of bioinformatics that not only is the amount of data increasing exponentially, but collaboration is also both widening and deepening among biologists, chemists, physicists, mathematicians, and c- puter scientists. The sheer volume of problems and databases requires - searchers to continually develop software packages in order to process the huge amounts of data, utilizing the latest mathematical methods. The - tent of this book is to provide a professional and in-depth treatment of the mathematical topics necessary in the study of bioinformatics. Artikel-Nr. 9783540748908

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