The Neuregulin-I/ErbB Signaling System in Development and Disease (Advances in Anatomy, Embryology and Cell Biology): Advances in Anatomy, Embryology and Cell Biology, Volume 190 - Softcover

Britsch, Stefan

 
9783540371052: The Neuregulin-I/ErbB Signaling System in Development and Disease (Advances in Anatomy, Embryology and Cell Biology): Advances in Anatomy, Embryology and Cell Biology, Volume 190

Inhaltsangabe

Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. Neuregulin signals are also involved in the development diseases including breast cancer, heart disease and the pathogenesis of schizophrenia. This book reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.

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Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. this signailing system has a wide range of functions during development of the nervous system, the heart, and the mammary gland. Furthermore, Neuregulin signals are also involved in the development of human diseases including breast cancer, heart disease and the pathogenesis of schizophrenia.

This monograph reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease. 

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9783540827481: The Neuregulin-I/ErbB Signaling System in Development and Disease

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ISBN 10:  354082748X ISBN 13:  9783540827481
Verlag: Springer, 2008
Softcover