Appropriate Dose Selection - How to Optimize Clinical Drug Development (Ernst Schering Foundation Symposium Proceedings, 59, Band 59) - Hardcover

 
9783540278672: Appropriate Dose Selection - How to Optimize Clinical Drug Development (Ernst Schering Foundation Symposium Proceedings, 59, Band 59)
Hardcover
ISBN 10: 3540278672 ISBN 13: 9783540278672
Verlag: Springer, 2006

Inhaltsangabe

Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to concurrent illnesses or co-medications. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. The continued use of biomarkers – based on the (known) pharmacology of the drug and/or biology of the underlying disease – along with exposure–response evaluation throughout all phases of drug development can quantitatively integrate clinical pharmacology knowledge, provide early proof of concept, and help in rational dose selection and rational drug product labeling for clinical use.

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Verlag
Springer
Erscheinungsdatum
2006
Sprache
Englisch
ISBN 10 
3540278672
ISBN 13 
9783540278672
Einband
Gebundene Ausgabe
Anzahl der Seiten
232
Herausgeber
Venitz J., Sittner W.
Kontakt zum Hersteller
ProductSafety@springernature.com
ProductSafety@springernature.com

Poststr. 9
Darmstadt
64293
Deutschland

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