Tying together technological and conceptual advances of the past decade, this seminal book introduces the novel approach of chemical cytometry -- the biochemical analysis of cell constituents at the single cell level. As such, it combines recently developed methods for the handling of single cells, the separation of their components, and the detection and analysis of biomolecular species with application examples from cell biology, neurobiology and molecular medicine.The editor has succeeded in acquiring contributions from the recognized leaders in the field, resulting in a complete and authoritative overview for both developers as well as users of these new methods.
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Chang Lu is an associate professor of chemical engineering at Virginia Tech, Blacksburg (USA). From 2004 to 2009 he was an assistant and associate professor of biological engineering at Purdue University at West Lafayette. He obtained his academic degrees from Peking University and from the University of Illinois at Urbana-Champaign, and received post-doctoral training at Cornell University. His research has been focused on Microfluidic devices for single cell analysis and tissue engineering. Professor Lu has received a number of awards, including the NSF Career Award and the Wallace H. Coulter foundation Early Career Award in Biomedical Engineering.
Tying together technological and conceptual advances oft he past decades, this seminal book introduces the novel approach of chemical cytometry - the biochemical analysis of cell constituents at the single cell level. As such, it combines recently developed methods for the handling of single cells, the separation of their components, and the detection and analysis of biomolecular species with application examples from cell biology, neurobiology and molecular medicine.
The editor has succeeded in acquiring contributions from the recognized leaders in the field, resulting in a complete and authoritative overview for both developers as well as users of these new methods.
From the Contents:
* Ultrasensitive detection of low-copy molecules from single cells
* Microfluidic technology for single-cell analysis
* On-chip electroporation and electrofusion for single-cell engineering
* Electrochemical determination of enzyme activity in single cells
* Single cell mass spectrometry
* Optical sensing arrays for single-cell analysis
* Metabolic cytometry and cell signaling studies
And many more.
Tying together technological and conceptual advances oft he past decades, this seminal book introduces the novel approach of chemical cytometry - the biochemical analysis of cell constituents at the single cell level. As such, it combines recently developed methods for the handling of single cells, the separation of their components, and the detection and analysis of biomolecular species with application examples from cell biology, neurobiology and molecular medicine.
The editor has succeeded in acquiring contributions from the recognized leaders in the field, resulting in a complete and authoritative overview for both developers as well as users of these new methods.
From the Contents:
* Ultrasensitive detection of low-copy molecules from single cells
* Microfluidic technology for single-cell analysis
* On-chip electroporation and electrofusion for single-cell engineering
* Electrochemical determination of enzyme activity in single cells
* Single cell mass spectrometry
* Optical sensing arrays for single-cell analysis
* Metabolic cytometry and cell signaling studies
And many more.
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