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Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology - Hardcover
Inhaltsangabe
This work is a review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: the structure, regulation and expression of the AP genes; the three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes; the phenotypic abnormalities of the different AP knockout mice; and our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.
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Über die Autorin bzw. den Autor
Jose Luis Millan received his early training in Clinical Chemistry at the University of Buenos Aires, Argentina and received pre-doctoral training at the La Jolla Cancer Research Foundation (the predecessor of the Burnham Institute) from 1977-1980. He completed his Ph.D. studies at the University of Umea, Sweden in 1983. After a period of postdoctoral training at the La Jolla Cancer Research Foundation he was appointed to the staff in 1986. He was promoted to Associate Professor in 1989 and to Professor in 1994 at that Institution. He also held the Chair of Medical Genetics at the Department of Medical Biosciences, School of Medicine, Umea University, Umea, Sweden from 1995 to 2000. Dr. Millan is currently Professor at The Burnham Institute and he maintains adjunct affiliations with Umea University and the Royal Academy of Medicine and Surgery, Murcia, Spain. Professor Millan has dedicated most of his scientific carrier to the understanding of the structure and biological functions of alkaline phosphatases during development and the significance of their re-expression in malignancy. This book highlights and discusses the major advances made in this field in the last 25 years.
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A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers:
* The structure, regulation and expression of the AP genes
* The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes
* The phenotypic abnormalities of the different AP knockout mice
* Our current understanding of the in vivo role of the AP isozymes.
The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.
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Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology
Verlag:
Wiley-VCH Verlag GmbH & Co. KGaA, 2006
ISBN 10: 3527310797
ISBN 13: 9783527310791
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hardcover. Zustand: Gut. 337 Seiten; 9783527310791.3 Gewicht in Gramm: 2. Artikel-Nr. 863610
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Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology
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Zustand: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions. Artikel-Nr. Z1-I-007-02150
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MAMMALIAN ALKALINE PHOSPHATASES: FROM BIOLOGY TO APPLICATIONS IN MEDICINE AND BIOTECHNOLOGY
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MAMMALIAN ALKALINE PHOSPHATASES: FROM BIOLOGY TO APPLICATIONS IN MEDICINE AND BIOTECHNOLOGY
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
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Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide. Artikel-Nr. ABNR-204441
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