This volume discusses the products of secondary metabolism such as coenzymes, antibiotics and immunosuppressants.
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Biotechnology Second, Completely Revised Edition Edited by H.-J. Rehm and G. Reed in cooperation with A. Pühler and P. Stadler This fully revised and expanded Second Edition takes into account all recent developments in biotechnology. It is extraordinarily broad in scope, up-to-date, carefully structured and well-balanced. "Biotechnology" considers both basic concepts and widely-differing industrial applications: it is a successful synthesis of theory and practice. Any scientist aiming for success in industrial microbiology, biochemistry, molecular biology and chemical engineering must turn to "Biotechnology". Volume 7: Products of secondary metabolism from fermentation and cell culture are mainly pharmaceuticals, ranging from traditional anti-bacterials like ß-lactams, new generation compounds like dalbaheptides and lantibiotics to immunomodulators and antitumor drugs. The major fields of application of these low volume/high price products are human and veterinary medicine as well as plant protection. In this volume functionally based screening approaches and the applications of molecular genetics in the discovery and process improvement of compounds are emphasized. Topics included are: • Novel Receptor-Active Compounds • Microbial Lipids • Microbial Siderophores • ß-Lactam Antibiotics • Peptide Antibiotics • Lantibiotics • Dalbaheptides • Aminoglycosides • Products from Basidiomycetes • Cyclosporins • Products from Plant Cells • Antitumor Agents
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