Asbestos and Mesothelioma (Current Cancer Research) - Softcover

Buch 15 von 24: Current Cancer Research
 
9783319851839: Asbestos and Mesothelioma (Current Cancer Research)
Softcover
ISBN 10: 3319851837 ISBN 13: 9783319851839
Verlag: Springer, 2018

Inhaltsangabe

This volume is comprised of a multidisciplinary assessment of the interplay between asbestos and cancer as well as new research about the biology and treatment of malignant mesothelioma.  Chapters on the various types of asbestos and other mineral fibers, epidemiology, history and future of asbestos-related diseases are included.  Other reviews present new information about the role of asbestos-related inflammation and genetic factors, including the role of inherited mutations of BAP1, in mesothelioma causation, as well as recent research about gene signatures, cell signaling, and epigenetic mechanisms in asbestos-related diseases.  Other chapters provide updates of novel disease biomarkers and prevention, mechanistic lesson from genetically engineered mouse and 3-D models of mesothelioma tumorigenesis and therapeutic resistance.  Also included are up-to-date reviews of surgical, molecularly targeted chemotherapeutic, and immunotherapeutic approaches for mesothelioma as well as an overview of legal issues.

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Über die Autorin bzw. den Autor

Joseph R. Testa, PhD, FACMG is Senior Member/Professor, Carol and Kenneth E. Weg Chair in Human Genetics, Chief of Laboratory Genetics, and Co-Leader of the Cancer Biology Program at Fox Chase Cancer Center, Philadelphia, PA. His research interests focus on mesothelioma pathogenesis and AKT-related oncogenesis. He has published numerous papers and reviews, and serves on the editorial boards of several journals, including as Senior Editor for Cancer Research. He has received multiple science awards, including the J. Christopher Wagner Medal from the International Mesothelioma Interest Group and the Pioneer Research Award from the Mesothelioma Applied Research Foundation. He is also a Fellow of the American Association for the Advancement of Science.

Von der hinteren Coverseite

This volume is comprised of a multidisciplinary assessment of the interplay between asbestos and cancer as well as new research about the biology and treatment of malignant mesothelioma.  Chapters on the various types of asbestos and other mineral fibers, epidemiology, history and future of asbestos-related diseases are included.  Other reviews present new information about the role of asbestos-related inflammation and genetic factors, including the role of inherited mutations of BAP1, in mesothelioma causation, as well as recent research about gene signatures, cell signaling, and epigenetic mechanisms in asbestos-related diseases.  Other chapters provide updates of novel disease biomarkers and prevention, mechanistic lesson from genetically engineered mouse and 3-D models of mesothelioma tumorigenesis and therapeutic resistance.  Also included are up-to-date reviews of surgical, molecularly targeted chemotherapeutic, and immunotherapeutic approaches for mesothelioma as well as an overview of legal issues.

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Verlag
Springer
Erscheinungsdatum
2018
Sprache
Englisch
ISBN 10 
3319851837
ISBN 13 
9783319851839
Einband
Taschenbuch
Anzahl der Seiten
416
Herausgeber
Testa Joseph R.
Kontakt zum Hersteller
ProductSafety@springernature.com
ProductSafety@springernature.com

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Darmstadt
64293
Deutschland

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9783319535586: Asbestos and Mesothelioma (Current Cancer Research)

Vorgestellte Ausgabe

ISBN 10:  3319535587 ISBN 13:  9783319535586
Verlag: Springer, 2017
Hardcover