The Functional Nucleus - Softcover

 
9783319817682: The Functional Nucleus
Softcover
ISBN 10: 331981768X ISBN 13: 9783319817682
Verlag: Springer, 2018

Inhaltsangabe

This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.

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Über die Autorin bzw. den Autor

David P. Bazett-JonesThe Hospital for Sick Children, Toronto, ON, Canada 
                Graham DellaireDalhousie University, Halifax, NS, Canada

Von der hinteren Coverseite

This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.

„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.

Verlag
Springer
Erscheinungsdatum
2018
Sprache
Englisch
ISBN 10 
331981768X
ISBN 13 
9783319817682
Einband
Taschenbuch
Anzahl der Seiten
519
Herausgeber
Bazett-Jones David P., Dellaire Graham
Kontakt zum Hersteller
Springer Nature Customer Service Center GmbH
ProductSafety@springernature.com

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Heidelberg
69115
Deutschland

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