Continuum Modeling in Mechanobiology - Hardcover

Über die Autorin bzw. den Autor

Larry Taber is a Senior Professor of Biomedical Engineering at Washington University in St. Louis. From 2007 until his retirement in 2017, he was the Dennis and Barbara Kessler Professor of Biomedical Engineering. Although his formal training is in aerospace engineering (B.A.E., Georgia Tech; Ph.D., Stanford University), he has published on a wide range of topics including cochlear mechanics, nonlinear shell theory, cardiovascular mechanics, and the mechanics of growth and development. Dr. Taber is a fellow of the American Society of Mechanical Engineers (ASME) and the American Institute for Medical and Biological Engineering. Three times he won the Richard Skalak Award for the best paper published in the Journal of Biomechanical Engineering, and in 2020 was awarded the H.R. LIssner Medal from ASME. From 2011-2016, he served as co-editor-in-chief of the journal Biomechanics and Modeling in Mechanobiology.

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This book reviews in detail the key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.

• Broadens readers' understanding of nonlinear elasticity, contractility, growth and remodeling theory, and mechanical feedback in development
• Includes numerous quantitative examples to illustrate basic theoretical mechanobiology concepts, such as active force generation, theories for growth and remodeling, and morphogenesis
• Illustrates theories with numerous applications to specific problems, such as cardiac mechanics, growth (and remodeling) of the heart and arteries, and embryonic development of the heart, brain, and gut