Cholesterol Modulation of Protein Function: Sterol Specificity and Indirect Mechanisms: 1115 (Advances in Experimental Medicine and Biology) - Hardcover

9783030042776: Cholesterol Modulation of Protein Function: Sterol Specificity and Indirect Mechanisms: 1115 (Advances in Experimental Medicine and Biology)

Hardcover

ISBN 10: 3030042774 ISBN 13: 9783030042776

Verlag: Springer, 2019

In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed.

This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function.

The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.

Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.

�ber die Autorin bzw. den Autor

Avia Rosenhouse-Dantsker, D.Sc., is a Clinical Assistant Professor at the University of Illinois at Chicago. Her research background ranges from quantum theory and computational biology to biophysical chemistry, molecular biology and electrophysiology. Her current research employs experimental and computational approaches to elucidate structural and functional mechanisms of protein modulation with a special emphasis on the modulation of ion channels by lipids (e.g. cholesterol, phosphoinositides, and others). Dr. Rosenhouse-Dantsker is a member of the Biophysical Society and the American Society for Biochemistry and Molecular Biology. She is currently also serving as a co-Editor on a book on the Direct Mechanisms in Cholesterol Modulation of Protein Function.

Anna N. Bukiya, Ph.D., is an Associate Professor at the Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center. Her scientific interests lie in the field of lipid modulation of ionic currents and ion channel sensitivity to alcohol starting from in utero development and spanning into adulthood. Current studies employ an array of computational, biochemical, electrophysiological, and integrative approaches. Dr. Anna Bukiya is a member of the Biophysical Society, and the American Society for Pharmacology and Experimental Therapeutics (Division of Cardiovascular Pharmacology). She is currently also serving as a co-Editor on a book on the Direct Mechanisms in Cholesterol Modulation of Protein Function.

Von der hinteren Coverseite

��ber diesen Titel� kann sich auf eine andere Ausgabe dieses Titels beziehen.

VerlagSpringer
Erscheinungsdatum2019
ISBN 10 3030042774
ISBN 13 9783030042776
EinbandTapa dura
SpracheEnglisch
Auflage1
Anzahl der Seiten212
HerausgeberRosenhouse-Dantsker Avia, Bukiya Anna N.
Kontakt zum HerstellerNicht verf�gbar

Neu kaufen

Diesen Artikel anzeigen

EUR 171,19

W�hrung umrechnen

Gratis f�r den Versand innerhalb von/der Deutschland

Versandziele, Kosten & Dauer

In den Warenkorb

Weitere beliebte Ausgaben desselben Titels

9783030042790: Cholesterol Modulation of Protein Function: Sterol Specificity and Indirect Mechanisms

Vorgestellte Ausgabe

ISBN 10: 3030042790 ISBN 13: 9783030042790
Verlag: Springer, 2019
Softcover

Suchergebnisse f�r Cholesterol Modulation of Protein Function: Sterol...

Foto des Verk�ufers

Cholesterol Modulation of Protein Function : Sterol Specificity and Indirect Mechanisms

Anna N. Bukiya

Verlag: Springer International Publishing, 2019

ISBN 10: 3030042774 ISBN 13: 9783030042776

Neu Hardcover

Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland

Verk�uferbewertung 5 von 5 Sternen

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function. The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems. Artikel-Nr. 9783030042776

Verk�ufer kontaktieren