Evolution's Destiny describes how biology and geochemistry have continually influenced each other in the co-evolution of the Earth and all life. Anyone with an interest in evolution, the environment, or natural history will find this a fascinating and inspiring read.
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Professor Bob Williams, MA, DPhil, FRS, is Emeritus Fellow at Wadham College and Emeritus Professor, University of Oxford. Born in 1926, he was educated at Wallasey Grammar School. He studied Chemistry at Merton College, Oxford, graduating in 1948. During the course of his Part II work the Irving-Williams series of the stabilities of complex ions, which is of paramount importance in both non-living and living systems, was discovered. He took his doctor's degree at Oxford in 1950 working with Professor H.M.N.H. Irving. With Professor A. Tiselius (Uppsala, Sweden) 1950-51, he developed certain (gradient elution) chromatographic methods of analysis. He then became lecturer and tutor in Chemistry at Wadham College, 1955-65. In 1961 he proposed proton-gradient-driven ATP formation as the driving force of bio-energetics. With C.S.G. Phillips, in 1996, he wrote a textbook of Inorganic Chemistry. After a year at Harvard University, 1965-66, with Professor B.L. Vallee, he changed to teach biochemistry until 1974. With Vallee he noted the entatic (constrained) state of atoms at enzyme sites. He became, successively, a Reader (1972) and Napier Royal Society Research Professor at the University of Oxford (1975-1991). He was elected Fellow of The Royal Society in 1972 and is a Foreign Member of the Swedish, Portugese, Czechoslovakian and Belgian science academies. He has given named lectures series in several European and North American Universities and numerous plenary international lectures at many Chemistry, Biochemistry and Biology Conferences. He is a medallist of the Biochemical Society (twice), The Royal Society (twice), The Royal Society of Chemistry (three times), The European Biochemical Societies (twice) and the International Union of Biochemistry. He has honorary degrees from Louvain, Leicester, Keel, Lisbon and East Anglia Universities. Bob Williams was a founder member of the Oxford Enzyme group in which he and his colleagues devised many new methods for the study of in vitro and in vivo biological systems, especially using nuclear magnetic resonance spectroscopy. He has recently co-edited a book on Chemistry at Oxford: A History from 1600-2005. He has been named as a Citizen of Honour by Oxford City and has an award from Oxford Preservation Trust for the effective creation of Sunnymead Park in North Oxford. He remains particularly proud of the success of his pupils in all walks of life. Professor Ros Rickaby is Professor of Biogeochemistry at the University of Oxford. Her main research themes include the environment, oceans and climate and lectures in the fundamentals of chemistry, stable isotope geochemistry and the evolutions of climate on long and short timescales.
Traditionally, evolution has been viewed solely from a biological fitness perspective, with genes determining how life takes shape in response to the environment. Furthermore, until the arrival of man, life had little or no apparent influence on the environment. Recent advances in our understanding of the Earth's geochemistry and knowledge of the geological record almost from the origin of the Earth have lead to the consideration that, beyond the "survival of the fittest" species, evolution has been occurring on larger, chemical, scale. This book demonstrates that biology and geochemistry have continually influenced each other in the co-evolution of the Earth and all life. In particular there were several essential controls over the bulk inorganic elements in cells which had major consequences later in evolution. The main driving change during evolution was that oxygen released from cells led to novel inorganic elements in the environment. The new elements then interacted with the cells and ultimately the cells came to utilise them in stages. The large scale changes of environmental chemicals ceased about 400 million years ago. At that time the chemical conditions of the environment for present-day life existed. Subsequent changes of organisms were by random "Darwinian" processes and led eventually to the development of a refined brain in man. Man has then been able to restart chemical and physical changes in the environment. The outcome of this remains unknown, but history implies that changes in living organisms must result from these novel chemical experiments with the environment. This highly original scholarly work will be of interest to chemists and biologists alike. Anyone with an interest in evolution, the environment, or natural history will find this a fascinating and inspiring subject.
Traditionally, evolution has been viewed solely from a biological fitness perspective, with genes determining how life takes shape in response to the environment. Furthermore, until the arrival of man, life had little or no apparent influence on the environment. Recent advances in our understanding of the Earth's geochemistry and knowledge of the geological record almost from the origin of the Earth have lead to the consideration that, beyond the "survival of the fittest" species, evolution has been occurring on larger, chemical, scale. This book demonstrates that biology and geochemistry have continually influenced each other in the co-evolution of the Earth and all life. In particular there were several essential controls over the bulk inorganic elements in cells which had major consequences later in evolution. The main driving change during evolution was that oxygen released from cells led to novel inorganic elements in the environment. The new elements then interacted with the cells and ultimately the cells came to utilise them in stages. The large scale changes of environmental chemicals ceased about 400 million years ago. At that time the chemical conditions of the environment for present-day life existed. Subsequent changes of organisms were by random "Darwinian" processes and led eventually to the development of a refined brain in man. Man has then been able to restart chemical and physical changes in the environment. The outcome of this remains unknown, but history implies that changes in living organisms must result from these novel chemical experiments with the environment. This highly original scholarly work will be of interest to chemists and biologists alike. Anyone with an interest in evolution, the environment, or natural history will find this a fascinating and inspiring subject.
Glossary, xv,
Abbreviations, xix,
About the Authors, xxi,
Chapter 1 Outline of the Main Chemical Factors in Evolution,
Chapter 2 Geological Evolution with Some Biological Intervention,
Chapter 3 Organism Development from the Fossil Record and the Chemistry of the Nature of Biominerals,
Chapter 4 Cells: Their Basic Organic Chemistry and their Environment,
Chapter 5 Other Major Elements in Organism Evolution,
Chapter 6 Trace Elements in the Evolution of Organisms and the Ecosystem,
Chapter 7 The Amalgamation of the Chemical and the Genetic Approaches to Evolution,
Subject Index, 308,
Outline of the Main Chemical Factors in Evolution
1.1 Introduction to the Chemistry of the Ecosystem
This chapter contains a general introduction to the multidisciplinary subject that includes chemistry, geochemistry, biochemistry and biology of the evolution of and on Earth, i.e. both the environment and its organisms. The book does depend heavily on chemistry so we give an outline of the principles of chemistry in this chapter for a reader who is not familiar with it as a discipline. Chemists may wish to skip quickly over Sections 1.2 to 1.6. In the minds of most scientists the evolution of organisms is based solely on organic chemicals, which quantitatively form by far the largest part of all living systems. In the book we wish to explore an additional part of this evolution, which in the first instance seems to be of little relevance to that of organisms. We refer to the early presence and the evolution of the inorganic surface of Earth, i.e. the atmospheric gases, the minerals and their solutions, mainly in the sea which, together, have formed the later changing environment for life. Here we consider these two parts of evolution, inorganic and organic, to be interacting in a common ecosystem. We will show that a major feature of life and its evolution, in addition to developing organic chemistry, is a changing availability and adopted essential use of selected inorganic chemical elements from this environment in cells. Many of these chemicals were dissolved from their minerals into solution (Table 1.1), increasingly by weathering, and then were taken into the cells of organisms. (A cell can be looked upon as an enclosed volume of space, in part permeable to particular chemicals.) Eventually these chemicals were returned to the environment, frequently in a transformed state. These elements perform one essential role in cellular catalysis – they are required to activate the small molecules, such as H2O, H2 and O2, and those in some organic metabolic cellular chemical reactions. The need for them follows from the fact that, although all organic chemicals are thermodynamically unstable relative to stable CO2, especially in the presence of the small molecules H2O and O2, they are generally kinetically quite stable at 20 °C. (Virtually all organic chemicals are kinetically unstable at >150 °C, particularly to hydrolysis and oxidation, implying that life has a restricted temperature range, that of liquid water, say from -10° to 150 °C.) At low temperature, 20 °C, they require energy input and catalysed activation in order to bring about synthesis, as well as catalysts for degradation. Therefore both energy and catalysts were required to activate organic chemicals before there could be any coded cellular chemistry, which we call life. The major catalytic inorganic ions are frequently strongly bound and of moderate or slow exchange rate in molecules. They are absolutely required. The essential role of other inorganic elements, which are poor catalysts, lies in their much weaker binding and fast exchange. These properties and the larger available quantities of these elements in the sea make them irreplaceable both in the management of osmotic and electrical balance of cells and in fast transfer of information, i.e. in message transmission necessary for balance between the several restricted paths of organic chemical change in cells. Later their fast transfer from outside to inside cells enabled organisms to respond quickly to rapid changes in their environment. The advantage of the exchange of some trace catalytic elements extended to their use in maintaining metabolic homeostasis inside cells. They also acted as controls of genetic expression in transcription factors.
A special chemical interest will be in the controlled biominerals (Table 1.2), produced by, even in, many organisms and giving rise to fossils, as well as those made by their decomposition as deposits on the surface of Earth after death, e.g. the White Cliffs of Dover in the south of England and the grains of some deserts, called diatomaceous earth. All these features of fossil and general biochemistry provide firm evidence of the coupled evolution of life with that of the surface of the Earth. We shall be led to propose that as well as the Darwinian random search amongst species of organisms for those of greatest survival value, associated with the small advantages of certain of them under given slowly changing environmental conditions, there was and is a systematic larger-scale evolution dependent upon the opportunities which the large-scale evolving chemical element environment provided. It is, we believe, this strong and faster environmental development, in a given chemical direction, that guided the way to today's organisms in a systematic, overall much slower, chemical evolution. However, the increasing complexity ruled out the possibility that they could manage it all, especially the novel oxidation chemistry and the original reductive chemistry in one compartment. As stress increased from oxidation it became necessary to produce different types of prokaryotes, bacteria, and in succession multicompartment then also multicellular organisms and mutually dependent organisms (symbiosis). Many of their evolving changes are seen in the inorganic chemical content of different organisms.
A particular problem we wish to tackle then is the changing role of the inorganic elements both in solution and in minerals in the evolution of the ecosystem. We shall observe that it is the waste by-products of the cellular organic chemistry, particularly oxygen, which initiated relatively quickly the major changes in environmental inorganic chemistry. The timing of the changes depended on their redox potential. We shall then show that it is the back-reaction of these changes which in turn affected the evolution of organisms. The two are in an interactive feedback system. In summary we have to examine the evolution of environmental and cellular inorganic with that of cellular organic/ inorganic chemistry. In doing so it is extremely helpful to follow initially the geological (inorganic) chemical record of all the minerals, especially that of sediments and their impurities. The minerals include fossils, the most clear-cut evidence of organism evolution available (see Chapter 3). To do so we divide the surface minerals of Earth into four classes. (i) Minerals formed without any intervention of solution or biological activity, for example on the solidification of melts, magma. (ii) Mineral sediments, formed later by weathering of rocks (see Table 1.1). (iii) Minerals which have arisen from chemical...
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