Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer (Advances in Medical Diagnosis, Treatment, and Care) - Hardcover

9781799835806: Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer (Advances in Medical Diagnosis, Treatment, and Care)

Hardcover

ISBN 10: 1799835804 ISBN 13: 9781799835806

Verlag: Medical Information Science Reference, 2021

In recent years, epidemiological studies have shown a significant increase of incidences regarding ulcerative colitis (UC) in most regions of the world. At present, a common therapeutic modality for inflammatory bowel disorders is the use of anti-inflammatory agents, including sulfasalazine and acetylsalicylic acid, steroid hormone, and other immunosuppressive agents. Most of these treatments are symptomatic and palliative because the etiology of the disease is not yet established. As a result of no proper drug available to treat UC, patients with UC are at a high risk of developing colitis-associated cancer (CAC). It is necessary to understand the genetic and molecular mechanisms involved in the pathogenesis of UC and CAC that lead to the path of new drug discoveries. Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer provides innovative insights that describe the fundamental understanding of UC and CAC and the molecular mechanisms behind the etiology as well as modern diagnostic methods that are employed in UC and CAC. Current prevention and therapeutic strategies practiced in the pre-clinical level are also discussed. The content within this publication examines alternative medicine and dietary intervention and drug delivery techniques. It is designed for healthcare professionals, physicians, academicians, researchers, R&D organizations, and medical students involved in drug discovery and clinical and therapeutic research.

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�ber die Autorin bzw. den Autor

Ashok Kumar Pandurangan is an Associate Professor working (August 2017 onwards) in the School of Life Sciences, B.S. Abdur Rahman Crescent Institute of Science and Technology, Vandalur, Chennai, India. Recently, he has been listed three times as one of the Top 2% of Scientists (2020-2022) in the field of Oncology and Toxicology by Stanford University, USA. He completed his Ph.D. in the Department of Biochemistry, University of Madras, Chennai, India, from 2006-2011. Later, he worked as a postdoctoral fellow in the Centre for Cancer Research, Children's Hospital Oakland Research Institute (California, USA), in the field of S1PLyase deficiency in colitis-associated cancer. Then he worked as a postdoctoral fellow in the Department of Nutrition and Dietetics, Universiti of Putra Malaysia (UPM), Serdang, Malaysia. Further, he worked as a Visiting Research Fellow in the Department of Pharmacology, University of Malaya, Kuala Lumpur, Malaysia. He published over 67 research and reviewed articles in peer-reviewed journals 5 books, and 27 book chapters. He received a Teachers Associateship Research Excellence (TARE) grant from SERB, India, in 2018 and several grants in Malaysia.

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