In the post-genomic era, science is still challenged to explain the biosynthesis of complex polysaccharides and glycoconjugates. Unlike nucleic acids and proteins, the information needed for their biosynthesis is not clearly contained to this day within the genome of the various organisms. This means that no biosynthetic code has been revealed yet. As a result, there will be millions of structurally distinct, functional chemical species at the end of their biosynthesis. This book offers an up-to-date view on sulfated polysaccharide structure and function state of the art in different life kingdoms: bacteria, protista, plantae, fungi and animalia. The structure, activities and current thinking on the interplay between these two vital features (as well as ways to study them) are reviewed in the present book. The growing economical interest in sulfated polysaccharides due to their potential biotechnological use in different areas, such as pharmaceutical and food industries, are also commented on. The information within the chapters adds to other prior available literature; the intention of the authors was to extend and further develop the discussions related to glycobiology.
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Miguel Gama received his Ph.D. in Biological Engineering at Minho University, in Portugal, in 1996. He is currently Associate Professor with Habilitation at Minho University, where he directs the FUNCARB Laboratory, a research group with about 20 researchers. He has authored/edited 4 books, over 100 papers in international journals, and 2 patents. Was the co-founder of a spinoff from Minho University, BNCTechnologies, dedicated to the development of applications for bacterial cellulose. His research interests include enzyme technology - enzymatic degradation of biomass - and the development of biomaterials, in particular bacterial cellulose, self-assembled amphiphilic nanogels and injectable hydrogels, aiming the development of applications for tissue regeneration and drug delivery.
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