Single Domain Antibodies: Methods and Protocols (Methods in Molecular Biology, 911, Band 911) - Hardcover

 
9781617799679: Single Domain Antibodies: Methods and Protocols (Methods in Molecular Biology, 911, Band 911)
Hardcover
ISBN 10: 161779967X ISBN 13: 9781617799679
Verlag: Humana, 2012

Inhaltsangabe

The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications.  In Single Domain Antibodies: Methods and Protocols, expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications. In Single Domain Antibodies: Methods and Protocols, expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Verlag
Humana
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
161779967X
ISBN 13 
9781617799679
Einband
Gebundene Ausgabe
Anzahl der Seiten
595
Herausgeber
Saerens Dirk, Muyldermans Serge
Kontakt zum Hersteller
preigu GmbH & Co. KG
mail@preigu.de

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