Tumor Models in Cancer Research (Cancer Drug Discovery and Development) - Hardcover

Buch 66 von 96: Cancer Drug Discovery and Development
 
9781607619673: Tumor Models in Cancer Research (Cancer Drug Discovery and Development)
Hardcover
ISBN 10: 1607619679 ISBN 13: 9781607619673
Verlag: Humana, 2010

Inhaltsangabe

The past 6 years since the first edition of this book have seen great progress in the development of genetically engineered mouse (GEM) models of cancer. These models are finding an important role in furthering our understanding of the biology of malignant disease. A comfortable position for GEM models in the routine conduct of screening for potential new therapeutics is coming more slowly but is coming. Increasing numbers of genetically engineered mice are available, some with conditional activation of oncogenes, some with multiple genetic changes providing mouse models that are moving closer to the human disease.

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Über die Autorin bzw. den Autor

Dr. Beverly A. Teicher is Senior Scientific Director in Cancer Research at Genzyme Molecular Oncology and Genzyme Corporation, Framingham, Massachusetts. She has authored or co-authored more than 400 scientific publications, has edited five books, senior editor for the journal Clinical Cancer Research and is series editor for the Cancer Drug Discovery and Development book series.

Von der hinteren Coverseite

Beverly A. Teicher and a panel of leading experts comprehensively describe the state-of-the-art in animal tumor model research. This volume updates and extends the comprehensive presentations in the first edition. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, and genetically engineered mouse models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research 2nd edition, provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.

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Verlag
Humana
Erscheinungsdatum
2010
Sprache
Englisch
ISBN 10 
1607619679
ISBN 13 
9781607619673
Einband
Gebundene Ausgabe
Auflage
2
Anzahl der Seiten
707
Herausgeber
Teicher Beverly A.
Kontakt zum Hersteller
preigu GmbH & Co. KG
mail@preigu.de

Lengericher Landstr. 19
Osnabrück
Niedersachsen
49078
Deutschland

Weitere beliebte Ausgaben desselben Titels

9781627038201: Tumor Models in Cancer Research (Cancer Drug Discovery and Development)

Vorgestellte Ausgabe

ISBN 10:  1627038205 ISBN 13:  9781627038201
Verlag: Humana, 2014
Softcover