Beginning from an engineering perspective and written for engineering students, this textbook presents applications in systems bioinformatics, the intersection of systems biology and bioinformatics. The approach adopted by the editors (both of Harvard Medical School) is to match familiar engineering ideas, such as analysis, design, and reverse engineering with their applications in systems bioinformatics. Thus, a section on signal processing addresses biological signal processing and signal processing methods for mass spectrometry, a section on control and systems explores modeling cellular networks, and a section on probabilistic data networks and communications contains chapters on topological analysis of biomolecular networks and on Bayesian networks for genetic analysis. Other topics addressed include fundamentals of design for synthetic biology, applied cellular engineering, DNA/RNA sequence hybridization, biomolecular computing and cryptography, and chemotaxis. The CD-ROM contains a variety of computer programs for data analysis, modeling, and other purposes. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)
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Gil Alterovitz is an NIH Biomedical Informatics Fellow in the Division of Health Sciences and Technology (HST) at Harvard and the Massachusetts Institute of Technology (MIT), and is a research affiliate at the Computer Science and Artificial Intelligence Laboratory (CSAIL) in the Department of Electrical Engineering and Computer Science at MIT. Marco F. Ramoni is an assistant professor of Pediatrics and Medicine at Harvard Medical School and an assistant professor of health sciences and technology at Harvard and the Massachusetts Institute of Technology (MIT).
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