Essential Concepts in Toxicogenomics (Methods in Molecular Biology, 460, Band 460) - Hardcover

 
9781588296382: Essential Concepts in Toxicogenomics (Methods in Molecular Biology, 460, Band 460)
Hardcover
ISBN 10: 1588296385 ISBN 13: 9781588296382
Verlag: Humana, 2008

Inhaltsangabe

Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity.- Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology.- Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications.- Role of Statistics in Toxicogenomics.- Predictive Toxicogenomics in Preclinical Discovery.- In Vivo Predictive Toxicogenomics.- Bioinformatics: Databasing and Gene Annotation.- Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics.- Toxicogenomics in Biomarker Discovery.- From Pharmacogenomics to Translational Biomarkers.- Public Consortium Efforts in Toxicogenomics.- Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations.

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The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field.  Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals.  Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology™ series format, this volume retains the practicality and usefulness of the highly successful series.

 

Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field.

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Verlag
Humana
Erscheinungsdatum
2008
Sprache
Englisch
ISBN 10 
1588296385
ISBN 13 
9781588296382
Einband
Gebundene Ausgabe
Anzahl der Seiten
288
Herausgeber
Mendrick Donna L., Mattes William B.
Kontakt zum Hersteller
Springer Nature Customer Service Center GmbH
ProductSafety@springernature.com

Europaplatz 3
Heidelberg
69115
Deutschland

Weitere beliebte Ausgaben desselben Titels

9781617376887: Essential Concepts in Toxicogenomics (Methods in Molecular Biology, Band 460)

Vorgestellte Ausgabe

ISBN 10:  1617376884 ISBN 13:  9781617376887
Verlag: Humana, 2010
Softcover