Antibody-Drug Conjugates: Methods and Protocols (Methods in Molecular Biology, Band 2078) - Softcover

Antibody-Drug Conjugates : Methods and Protocols

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume looks at key methodologies that are commonly used across antibody drug conjugates (ADCs) programs. The chapters in this book cover topics such as conjugations to endogenous cysteine residues; click chemistry conjugations; antibody conjugations via glycosyl remodeling; analysis of ADCs by native mass spectrometry; characterization of ADCs by capillary electrophoresis; LC/MS methods for studying lysosomal ADC catabolism; and determination of ADC concentration by ligand-binding assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Antibody-Drug Conjugates: Methods and Protocols is a valuable resource that aims to lower the 'activation barrier' when undertaking a new discipline, and provides a 'toolbox' for the next generation of ADC scientists. Artikel-Nr. 9781493999316

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