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Mitochondria and Cell Death (Cell Death in Biology and Diseases) - Softcover

 
9781493980949: Mitochondria and Cell Death (Cell Death in Biology and Diseases)
Softcover
ISBN 10: 1493980947 ISBN 13: 9781493980949
Verlag: Humana, 2018

Inhaltsangabe

This volume examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mitochondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mitochondria and other cellular components, including the important role of mitochondria in antiviral immunity. The expertly authored chapters are drawn from multidisciplinary international perspectives, lending a nuanced and comprehensive approach to the material.
 
Mitochondria and Cell Death, part of the Cell Death in Biology and Diseases series, is invaluable reading for graduate students, researchers, and clinicians in the fields of neuroscience, oncology, gastroenterology, and hepatology,as well as those interested in the study of mitochondria and cell biology.


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Über die Autorin bzw. den Autor

David M. Hockenbery, MD is Professor, Member & Head of the Gastroenterology & Hepatology Section of the Fred Hutchinson Cancer Research Center, Seattle Cancer Care Alliance. He is also a Mentor in the Seattle Children’s/UW/Hutchinson Center Pediatric Hematology-Oncology Fellowship Program. He received his M.D. from Washington University in St. Louis, completed his Residency in Medicine at Johns Hopkins and also completed two Fellowships, in Gastroenterology and Molecular Oncology, at Washington University. Dr. Hockenbery’s current research interests include the bcl-2 oncogene and its role in apoptosis, mitochondrial biology and bioenergetic metabolism, utilizing cell culture, transgenic mouse and protein biochemistry approaches for identification of cancer-selective metabolic pathways and discovery of small molecule inhibitors targeting these pathways.

Von der hinteren Coverseite

This volume examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mitochondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mitochondria and other cellular components, including the important role of mitochondria in antiviral immunity. The expertly authored chapters are drawn from multidisciplinary international perspectives, lending a nuanced and comprehensive approach to the material.
 
Mitochondria and Cell Death, part of the Cell Death in Biology and Diseases series, is invaluable reading for graduate students, researchers, and clinicians in the fields of neuroscience, oncology, gastroenterology, and hepatology,as well as those interested in the study of mitochondria and cell biology.

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Verlag
Humana
Erscheinungsdatum
2018
Sprache
Englisch
ISBN 10 
1493980947
ISBN 13 
9781493980949
Einband
Taschenbuch
Anzahl der Seiten
248
Herausgeber
Hockenbery David M.
Kontakt zum Hersteller
Springer-Verlag GmbH
customerservice@springernature.com

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Deutschland