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Metabolic Network Reconstruction and Modeling: Methods and Protocols (Methods in Molecular Biology) - Hardcover
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<DIV>THIS VOLUME LOOKS AT THE LATEST METHODOLOGIES USED TO STUDY CELLULAR METABOLISM WITH IN SILICO APPROACHES. THE CHAPTERS IN THIS BOOK ARE DIVIDED INTO 3 PARTS: PART I DISCUSSES TOOLS AND METHODS USED FOR METABOLIC RECONSTRUCTIONS AND BASIC CONSTRAINT-BASED METABOLIC MODELING (CBMM); PART II EXPLORES PROTOCOLS FOR THE GENERATION OF EXPERIMENTAL DATA FOR METABOLIC RECONSTRUCTION AND MODELING, INCLUDING TRANSCRIPTOMICS, PROTEOMICS, AND MUTANT GENERATIONS; AND PART III COVER ADVANCED TECHNIQUES FOR QUANTITATIVE MODELING OF CELLULAR METABOLISM, INCLUDING DYNAMIC FLUX BALANCE ANALYSIS AND MULTI-OBJECTIVE OPTIMIZATION. WRITTEN IN THE HIGHLY SUCCESSFUL<I> METHODS IN MOLECULAR BIOLOGY</I> SERIES FORMAT, CHAPTERS INCLUDE INTRODUCTIONS TO THEIR RESPECTIVE TOPICS, LISTS OF THE NECESSARY MATERIALS AND REAGENTS, STEP-BY-STEP, READILY REPRODUCIBLE LABORATORY PROTOCOLS, AND TIPS ON TROUBLESHOOTING AND AVOIDING KNOWN PITFALLS.<BR/></DIV><DIV><BR/></DIV><DIV>CUTTING-EDGE AND THOROUGH, <I>METABOLIC NETWORK RECONSTRUCTION AND MODELING: METHODS AND PROTOCOLS</I> IS A VALUABLE RESOURCE FOR QUALIFIED INVESTIGATORS STUDYING CELLULAR METABOLISM, AND NOVICE RESEARCHERS WHO WANT TO START WORKING WITH CBMM.</DIV><DIV><BR/></DIV>
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This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Metabolic Network Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM.
Biografía del autor:
Cutting-edge and thorough, Metabolic Network Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM.
Marco Fondi
Department of Biology
University of Florence
Via Madonna del Piano 6, I-50019 Sesto Fiorentino, Italy
Email: marco.fondi@unifi.it
Department of Biology
University of Florence
Via Madonna del Piano 6, I-50019 Sesto Fiorentino, Italy
Email: marco.fondi@unifi.it
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- VerlagHumana Press
- Erscheinungsdatum2017
- ISBN 10 1493975277
- ISBN 13 9781493975273
- EinbandTapa dura
- Auflage1
- Anzahl der Seiten424
- HerausgeberFondi Marco
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Buchbeschreibung Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, MetabolicNetwork Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM. Artikel-Nr. 9781493975273
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