Gene Essentiality: Methods and Protocols (Methods in Molecular Biology, 1279, Band 1279) - Hardcover

 
9781493923977: Gene Essentiality: Methods and Protocols (Methods in Molecular Biology, 1279, Band 1279)
Hardcover
ISBN 10: 1493923978 ISBN 13: 9781493923977
Verlag: Humana, 2015

Inhaltsangabe

This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans. Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon mutagenesis data, as well as databases and servers that are often used in studying gene essentiality. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and up-to-date, Gene Essentiality: Methods and Protocols will aid researchers who wish to further our knowledge in this vital field of study.

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Von der hinteren Coverseite

This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans. Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon mutagenesis data, as well as databases and servers that are often used in studying gene essentiality. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and up-to-date, Gene Essentiality: Methods and Protocols will aid researchers who wish to further our knowledge in this vital field of study.

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Verlag
Humana
Erscheinungsdatum
2015
Sprache
Englisch
ISBN 10 
1493923978
ISBN 13 
9781493923977
Einband
Gebundene Ausgabe
Anzahl der Seiten
259
Herausgeber
Lu Long Jason
Kontakt zum Hersteller
Springer-Verlag GmbH
customerservice@springernature.com

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Heidelberg
Baden-Württemberg
69121
Deutschland

Weitere beliebte Ausgaben desselben Titels

9781493948628: Gene Essentiality: Methods and Protocols (Methods in Molecular Biology, Band 1279)

Vorgestellte Ausgabe

ISBN 10:  1493948628 ISBN 13:  9781493948628
Verlag: Humana, 2016
Softcover