The Science of Reconstructive Transplantation (Stem Cell Biology and Regenerative Medicine) - Hardcover

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Gerald Brandacher is Scientific Director of the Johns Hopkins Composite Tissue Allotransplantation (CTA) program. He is also an Associate Professor of surgery at the Department of Plastic and Reconstructive Surgery at Johns Hopkins University School of Medicine. Prior to joining Johns Hopkins in 2010, Dr. Brandacher was a Key Member of the hand transplant programs in Innsbruck, Austria, and at the University of Pittsburgh, where he headed the nation's first double hand transplant surgery and the first forearm transplant surgery. He was also instrumental in designing a novel cell-based immunomodulatory treatment protocol for CTA. His main scientific interests are donor-specific immune tolerance and immunomonitoring strategies and he has published extensively.

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This volume presents a comprehensive overview of the latest advances in basic and translational research in the field of reconstructive transplantation and its potential therapeutic implications. Dr. Thomas E. Starzl and Dr. Raimund Margreiter, both pioneers in the field of transplantation, have written forewords for the book.

The volume spans such topics as skin rejection, immune monitoring, stem cell-based immunomodulatory strategies, costimulatory blockade, tolerance induction, chronic rejection, ischemia reperfusion injury, nerve regeneration, cortical reintegration, and small and large animal models for reconstructive transplantation. The book is intended for biomedical researchers and basic scientists in the field of reconstructive transplantation, transplant immunology and regenerative medicine, as well as clinicians, surgeons and multidisciplinary specialists, who are practicing or interested in this novel and exciting field. Postgraduate fellows and students will also find it a valuable reference.