Mathematical and Statistical Methods for Genetic Analysis - Softcover

Inhaltsangabe

1 Basic Principles of Population Genetics.- 2 Counting Methods and the EM Algorithm.- 3 Newton's Method and Scoring.- 4 Hypothesis Testing and Categorical Data.- 5 Genetic Identity Coefficients.- 6 Applications of Identity Coefficients.- 7 Computation of Mendelian Likelihoods.- 8 The Polygenic Model.- 9 Markov Chain Monte Carlo Methods.- 10 Reconstruction of Evolutionary Trees.- 11 Radiation Hybrid Mapping.- 12 Models of Recombination.- 13 Poisson Approximation.- Appendix: Molecular Genetics in Brief.- A.l Genes and Chromosomes.- A.2 From Gene to Protein.- A.3 Manipulating DNA.- A.4 Mapping Strategies.- References.

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