Kynurenine and Serotonin Pathways: Progress in Tryptophan Research - Softcover

Inhaltsangabe

Session I. Tryptophan and its Metabolites: Chemical and Analytical Issues.- Retro-, Intro- and Perspectives of Trypto-Fun.- Tryptophan and Related Alkaloids.- Stability of Tryptophan in Peptides Against Oxidation and Irradiation.- Mass Spectrometric Determinations of Tryptophan and its Metabolites.- Signal-to-Noise Optimization of HPLC-Fluorometric Systems and their Application to the Analysis of Indoles.- Brain Indole Metabolism Assessed Using in vivo Dialysis.- Sub-Picogram Determination of Serotonin Using HPLC with Electrochemical Detection for Microdialysis Studies of Serotonin Release.- Session II. Tryptophan Metabolism: Serotonin and Melatonin.- Autoradiographic Measurement of the Rate of Serotonin Synthesis in the Rat Brain.- Autoradiographic Studies of 5HT2 Receptors.- Ambivalence on the Multiplicity of Mammalian Aromatic L-Amino Acid Decarboxylase.- Interrationships of DNA Cycles and Melatonin Synthesis.- Regulation of Melatonin Synthesis in the Ovine Pineal Gland.- Melatonin Synthesis: Multiplicity of Regulation.- Session III. Tryptophan Metabolism: Kynurenines.- The Role of Tryptophan and Kynurenine Transport in the Catabolism of Tryptophan Through Indoleamine 2,3-Dioxygenase.- Kynureninase and Kynurenine 3-Hydroxylase in Mammalian Tissues.- Relationships Between Pteridine Synthesis and Tryptophan Degradation.- Quinolinic acid and Kynurenic acid in the Mammalian Brain.- Kynurenate Forming Enzymes in Liver, Kidney and Brain.- Regulation of Pyridine Nucleotide Coenzyme Metabolism.- Session IV. Biological Effects: Serotonin and Melatonin.- Serotonin: Its Role and Receptors in Enteric Neurotransmission.- Mechanisms of Serotonergic Affect Control.- Neuroendocrine Responses to L-Tryptophan as an Index of Brain Serotonin Function: Effect of Weight Loss.- Melatonin Receptors in the Central Nervous System.- Melatonin Interaction With the Benzodiazepine-GABA Receptor Complex in the CNS.- Session V. Biological Effects: Tryptophan and Kynurenines.- Effects of Tryptophan 2,3-Dioxygenase Inhibitors in the Rat.- Bidirectional Relationships Between Tryptophan and Social Behavior in Vervet Monkeys.- The Regulation of Brain Kynurenic Acid Content: Focus on Indole-3-Pyruvic Acid.- Physiological Role of 3-Hydroxykynurenine and Xanthurenic Acid Upon Crustacean Molting.- Kynurenines in the Regulation of Behavior in Insects.- Effects of Quinolinic and Kynurenic Acids on Central Neurons.- Behavioral Abnormalities in Rats After Single Treatment with Quinolinic Acid During Early Ontogenesis.- Tryptophan Nutrition and Metabolism: An Overview.- Comparison of Tryptophan Metabolism In Vivo and in Isolated Hepatocytes from Vitamin B6 Deficient Mice.- Effects of the Diet and other Metabolic Phenomena on Brain Tryptophan Uptake and Serotonin Synthesis.- Effects of Tryptophan and of 5-Hydroxytryptamine Receptor Subtype Agonists of Feeding.- The Role of Serotonin (5-HT) in Feeding Responses to Amino Acids.- Session VII. Clinical Aspects.- Cardiovascular and Endocrine Properties of L-Tryptophan in Combination With Various Diets.- Acute Effects of Meals on Brain Tryptophan and Serotonin in Humans.- Implications of Interferon-induced Tryptophan Catabolism in Cancer, Autoimmune Diseases and AIDS.- Induction of Indoleamine 2,3-Dioxygenase in Tumor Cells Transplanted into Allogeneic Mouse: Interferon-? is the Inducer.- Short Communications.- Plasma Free 5HT, Plasma 5HIAA and Whole Blood 5HT in the Rat.- Effects of Clomipramine on Extracellular Serotonin in the Rat Frontal Cortex.- Tryptophan Metabolism in Senile Cataract Assessed Patients by High-Performance Liquid Chromatography.- The Effect of Aluminum on Rat Brain and Liver Quinolinic Acid Concentrations.- Kynurenine and Lipid Metabolism.- Content of Tryptophan in Human Hair.- Detection of a New Intermediate Product of Indolealkylamine Metabolism in the Brain.- The Excretion of N1-Methyl-2-pyridone-5-carboxylic Acid and Related Compounds in Human Subjects After Oral Administration of Nicotinic Acid, Tri

Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.