Immunology of Human Infection - Softcover

Inhaltsangabe

Viruses.- 1 Immunology of Poxviruses.- 1. Introduction.- 2. General Features of Poxviruses.- 2.1. Biological Properties.- 2.2. Pathogenesis.- 2.3. Persistent Infections.- 2.4. Postinfectious Encephalitis.- 2.5. Relationship to Multiple Sclerosis.- 3. Poxvirus Antigens.- 4. Humoral Immune Responses to Poxvirus Infection.- 4.1. General Considerations.- 4.2. Neutrahzing Antibodies and Protective Immunity.- 5. Cellular Immune Responses to Poxvirus Infection.- 5.1. General Considerations.- 5.2. T-Cell-Mediated Virus Clearance.- 5.3. T-Cell Migration and Recruitment.- 5.4. Requirements for Virus-Specific Cytolysis by T Cells.- 5.5. Requirements for Induction of Virus-Specific Cytotoxic T Cells.- 5.6. T-Cell Memory.- 6. Vaccination and Passive Immunity.- 7. Concluding Remarks.- References.- 2 Immunology of Herpes Simplex Viruses.- 1. Introduction.- 2. Virus Proteins and Antigens.- 3. Interactions between HSV and the Immune System.- 3.1. In Vitro Interactions.- 3.2. In Vivo Interactions.- 4. Transformation with HSV.- 5. Immunopathological Disease.- 6. Diagnostic Aspects.- 7. Immunoprevention and Immunotherapy.- 7.1. Vaccines.- 7.2. Other Agents.- 8. Envoi.- References.- 3 Immunology of Varicella-Zoster Virus.- 1. Introduction.- 1.1. Relative Clinical Importance.- 1.2. History.- 1.3. Evolutionary Aspects.- 2. Viral Properties.- 2.1. Pathogenesis of Disease.- 2.2. Immune Responses vs. Viral Antigen.- 3. Host Factors: Clinical Observations.- 3.1. Normal Host.- 3.2. The Compromised Host.- 3.3. Virus-Host Relationship.- 4. Cell-Mediated Immunity.- 4.1. In Vivo.- 4.2. In Vitro.- 5. Humoral Immunity.- 5.1. Serum Antibody.- 5.2. Laboratory Methods.- 5.3. Secretory Antibody.- 6. Ontogeny of the Immune Response.- 7. Treatment.- 7.1. Prevention.- 7.2. Antiviral Chemotherapy.- 7.3. Immunotherapy.- References.- 4 Immunology of Cytomegalovirus.- 1. Introduction.- 2. Microbial Aspects.- 2.1. Virus Characteristics.- 2.2. Strain Variation.- 3. Host Factors.- 3.1. Genetics.- 3.2. Geography.- 4. Microbial-Host Interactions.- 4.1. Acquired Infection.- 4.2. Congenital and Neonatal Infection.- 4.3. Special Hosts.- 5. Immunodiagnosis.- 6. Immunoprevention.- 7. Immunotherapy.- Addendum.- References.- 5 Immunology of Epstein-Barr Virus.- 1. Virological Aspects.- 2. EBV-Host Interactions.- 2.1. EBV-Associated Antigen-Antibody Systems.- 2.2. EBV-Associated Immune Reactions in the General Population.- 2.3. EBV-Associated Immune Reactions in Infectious Mononucleosis.- 2.4. EBV-Associated Immune Reactions in Burkitt's Lymphoma.- 2.5. EBV-Associated Immune Reactions in Nasopharyngeal Carcinoma.- 2.6. EBV-Associated Immune Reactions in Other Diseases.- 2.7. Hypothetical Modes of EBV-Host Interactions.- 3. Immunodiagnosis, Immunoprevention, and Immunotherapy.- References.- 6 Immunology of Measles, Mumps, and Rubella Viruses.- 1. General Introduction.- 2. Measles.- 2.1. Epidemiology.- 2.2. Virological Aspects.- 2.3. Host-Virus Interaction.- 2.4. Diagnosis.- 2.5. Immunoprevention and Immunotherapy.- 3. Mumps.- 3.1. Epidemiology.- 3.2. Virological Aspects.- 3.3. Aspects of the Host-Virus Interaction.- 3.4. Diagnosis.- 3.5. Immunoprevention and Therapy.- 4. Rubella.- 4.1. Epidemiology.- 4.2. Virological Aspects.- 4.3. Host-Viral Interaction.- 4.4. Immunodiagnosis.- 4.5. Immunoprevention and Therapy.- References.- 7 Immunology of Respiratory Viruses.- 1. Introduction.- 2. Host-Parasite Interaction.- 2.1. Primary Defense Mechanisms.- 2.2. Infection by Aerosols.- 2.3. Immune Apparatus of the Respiratory Tract.- 2.4. Immunophysiological Changes following Respiratory Viral Infection.- 2.5. Local Nature of Antibody Production.- 2.6. Specificity.- 2.7. Cellular Immunity and Respiratory Infection.- 3. Immune Response to Specific Respiratory Viruses.- 3.1. Adenoviruses.- 3.2. Rhino viruses.- 3.3. Respiratory Syncytial Virus.- 3.4. Parainfluenza and Influenza Viruses.- 3.5. Coronaviruses.- 4. Immunodiagnosis.- 5. Immunoprevention: Vaccination.- 5.1. Direct Application.- 6. Immuno

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