Calcium is crucial in governing contractile activities of myofilaments in cardiomyocytes, any defeats in calcium homeostasis of the cells would adversely affect heart pumping action. The characterization of calcium handling properties in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMCs) is of significant interest and pertinent to the stem cell and cardiac regenerative field because of their potential patient-specific therapeutic use.
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The principle author, Dr. Lee Yee-Ki, is a PhD graduate in the University of Hong Kong. Her research interests focus on hypertrophy signal-driven cardiac differentiation and stem cell-derived cardiomyocytes maturation. Her interest was further extrapolated to maturity of hiPSC-CMC by studying comparing calcium homeostasis with human embryonic stem cell (hESC)-CMC. She has altogether 10 papers in stem cell related field with 4 as primary author in international journals like Molecular Endocrinology and Stem Cell Reviews.
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Taschenbuch. Zustand: Neu. Neuware -Calcium is crucial in governing contractile activities of myofilaments in cardiomyocytes, any defeats in calcium homeostasis of the cells would adversely affect heart pumping action. The characterization of calcium handling properties in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMCs) is of significant interest and pertinent to the stem cell and cardiac regenerative field because of their potential patient-specific therapeutic use.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 64 pp. Englisch. Artikel-Nr. 9781461440925
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Taschenbuch. Zustand: Neu. Calcium Handling in hiPSC-Derived Cardiomyocytes | Siu Chung-Wah (u. a.) | Taschenbuch | xii | Englisch | 2012 | Springer US | EAN 9781461440925 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Artikel-Nr. 106538469
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