Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics (Cancer Drug Discovery and Development) - Hardcover

Buch 69 von 96: Cancer Drug Discovery and Development
 
9781461405979: Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics (Cancer Drug Discovery and Development)
Hardcover
ISBN 10: 1461405971 ISBN 13: 9781461405979
Verlag: Humana, 2011

Inhaltsangabe

The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.

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The insulin-like growth factor system has been shown to play a critical role in cancer development and progression. Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics, specifically brings these aspects to the reader. The volume covers the epidemiological aspects of the relationships between circulating insulin and IGF-1 levels and the risk for cancer and cancer-related mortality and in particularly in disease states such as obesity and Type 2 diabetes. It then addresses the basic biology of the system and how the ligands, receptors and IGF-binding proteins affect cancer cell biology and cancer progression. Finally, it discusses the therapeutic potential of inhibiting the receptors using various newly discovered monoclonal antibodies and tyrosine kinase inhibitors that are in preclinical and clinical trials.

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Verlag
Humana
Erscheinungsdatum
2011
Sprache
Englisch
ISBN 10 
1461405971
ISBN 13 
9781461405979
Einband
Gebundene Ausgabe
Anzahl der Seiten
296
Herausgeber
LeRoith Derek
Kontakt zum Hersteller
preigu GmbH & Co. KG
mail@preigu.de

Lengericher Landstr. 19
Osnabrück
Niedersachsen
49078
Deutschland

Weitere beliebte Ausgaben desselben Titels

9781461429623: Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics (Cancer Drug Discovery and Development)

Vorgestellte Ausgabe

ISBN 10:  1461429625 ISBN 13:  9781461429623
Verlag: Humana, 2013
Softcover