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Principles of Molecular Diagnostics and Personalized Cancer Medicine - Hardcover

Tan, Dongfeng; Lynch, Henry T.

 
9781451131970: Principles of Molecular Diagnostics and Personalized Cancer Medicine

Inhaltsangabe

Principles of Molecular Diagnostics and Personalized Cancer Medicine"

>Improve your understanding of…
• The basic mechanisms of carcinogenesis— including material on cell proliferation, signal transduction pathways, cancer stem cells, and the interaction between genetics and environmental factors.
• The most current molecular techniques —including polymerase chain reaction (PCR) technique, single nucleotide polymorphisms, cancer cytogenomics and epigenetics, whole-genome assessments, and next- generation sequencing.
• Molecular tests —including molecular screening, minimal residual disease detection, circulating tumor cell tests, molecular tumor staging, and molecular cancer prognosis assessment.
• Imaging and screening technologies —including molecular imaging, genetic tests, biostatistics, and bioinformatics.
• The molecular basis of therapy —including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles.
• Molecular diagnostics – including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management.
• Targeted treatment – including personalized medicine and targeted therapy for commonly occurring malignancies— plus insights on new approaches to targeted drug discovery and the future of molecular oncology!

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