This volume reviews the most recent advances in the understanding of cellular and molecular mechanisms for immune responses and immune regulation. Chapters in the first portion of this book discuss the theoretical basis for current immunotherapies for autoimmune diseases. The second portion of the book provides an updated review on the research behind the clinical trials/immunotherapies (e.g. T-cell vaccination, antibody therapy, etc.) in the areas of autoimmune diseases by the principal investigators of these studies. These chapters discuss clinical and basic research as well as immunological data in the context of cellular and molecular mechanisms of the therapies. The book finishes with chapters by leaders in the field who provide expert views on challenges and future directions. The book’s editor is well-known internationally, particularly in the field of multiple sclerosis and T-cell vaccination as a potential treatment of multiple sclerosis.
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This comprehensive volume assembles the insights and experience of over twenty experts and thought leaders in the field of autoimmune disease and immunotherapy. These discussions represent some of the newest concepts in autoimmune mechanisms and an array of new treatments that would have been considered science fiction only two decades ago. This book provides a wide-ranging review of two main arenas of current research: that of autoimmune mechanisms of disease and that of the latest developments in immunotherapy, with an emphasis upon multiple sclerosis. The conclusions reached by these authors will influence our thinking about autoimmune disease mechanisms and our methods of patient treatment in one of the fastest developing areas of modern medicine. Immune Regulation and Immunotherapy in Autoimmune Disease is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of immunology, microbiology, infectious disease, virology, pharmacology, and medicine.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book critically reviews both clinical and immunological aspects of auto- mune disease with a strong emphasis on multiple sclerosis (MS). Research in MS is one of the fastest-developing areas in modern medicine. It employs some of the newest concepts in autoimmune mechanisms and an array of new treatments that would have been considered science fiction only two decades ago. It is an area in which research findings are being actively translated into treatment strategies. Advances in this area have both clinical and scientific implications for other autoimmune conditions that share many similarities with MS. The book, which comprises 24 chapters contributed by experts and thought leaders in the field, is designed to provide new insights into two arenas: our current understanding of autoimmune mechanisms and immune regulation and the latest developments in immunotherapy. This book is intended for both researchers and clinicians. Its purpose is not only to provide a comprehensive review on the recent advances in the two arenas m- tioned above but also to reflect the current opinions or concepts that influence our thinking about the disease mechanisms and our way of treating MS patients. Many of these issues have emerged from recent studies and are somewhat contradictory to traditional thinking. For example, recent studies have indicated that MS is more heterogeneous in many aspects than traditionally thought. Pathologically, in ad- tion to demyelination and inflammation, there is axonal loss or damage detectable in the central nervous system (CNS) lesions. Artikel-Nr. 9781441942098
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